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10.7754/Clin.Lab.2020.200850

http://scihub22266oqcxt.onion/10.7754/Clin.Lab.2020.200850
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33180450!ä!33180450

suck abstract from ncbi


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pmid33180450      Clin+Lab 2020 ; 66 (11): ä
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  • Chembio DPP COVID-19 IgM/IgG Serological Testing: Laboratory Validation, Guidelines, and Recommendations #MMPMID33180450
  • Bardarov S; Cesare J; Kopolovich H; Otterbeck P; LaBarbera M; Nfonoyim J; Salhany R; Rotatori F; Mantello G
  • Clin Lab 2020[Nov]; 66 (11): ä PMID33180450show ga
  • BACKGROUND: On January 30, 2020, WHO declared COVID-19 a pandemic. In this article we describe our experience at Richmond University Medical Center with Chembio serological IgM, IgG testing. METHODS: In this prospective cohort study of patients and hospital employees, we utilized Chembio COVID-19 IgM/IgG serological testing in addition to Cepheid RT-PCR analysis. RESULTS: We evaluated the performance of Chembio serological test for IgM and IgG as an employee screening tool in a community hospital setting. The total number of currently asymptomatic employees screened was 1,866 from the Richmond University Medical Center. The non-exposed group included 1,253 (67.1%) employees with no significant clinical history and non-reactive IgM and IgG antibodies. The convalescent group included 255 (13.7%) of the employees with elevation of IgG only, 18 (1%) employees with past history of positive PCR and COVID-19 who currently have non-reactive IgM and IgG antibodies or demonstrate elevated IgG only, followed by 3 employees (< 1%) with no past clinical history who demonstrated reactive IgM and IgG antibodies and negative follow up by PCR. The reported 14.9% exposure/convalescent rate is lower than the reported 20% by the Department of Health and Governor Andrew Cuomo and may represent a better utilization of personal protective equipment, better hand washing techniques, and better disinfection procedures combined with strict social distancing. CONCLUSIONS: Chembio's performance is satisfactory; however, hospitals must design their own policies addressing: who needs to be screened and who will interpret the results as well as constructing management algorithms for employees with no previous history and current double positive antibodies.
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/*methods[MESH]
  • |Coronavirus Infections/blood/diagnosis[MESH]
  • |Guidelines as Topic[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/*analysis[MESH]
  • |Immunoglobulin M/*analysis[MESH]
  • |Mass Screening/*methods[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/blood/diagnosis[MESH]


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