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10.1055/a-1296-7935

http://scihub22266oqcxt.onion/10.1055/a-1296-7935
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33176367!8043595!33176367
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suck abstract from ncbi

pmid33176367      Drug+Res+(Stuttg) 2021 ; 71 (3): 166-170
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  • Favipiravir and COVID-19: A Simplified Summary #MMPMID33176367
  • Ghasemnejad-Berenji M; Pashapour S
  • Drug Res (Stuttg) 2021[Mar]; 71 (3): 166-170 PMID33176367show ga
  • A recent outbreak of coronavirus disease 2019 (COVID-19) caused by the novel coronavirus designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in Wuhan, China, at the end of 2019 and then spread rapidly all over the world. However, there are no specific antiviral therapies for COVID-19, using the agents which approved or in development for other viral infections is one of the potentially quickest ways to find treatment for this new viral infection. Favipiravir is an effective agent that acts as a nucleotide analog that selectively inhibits the viral RNA dependent RNA polymerase or causes lethal mutagenesis upon incorporation into the virus RNA. In view of recent studies and discussion on favipiravir, in this mini review we aimed to summarize the clinical trials studying the efficacy and safety of favipiravir in patients with COVID-19.
  • |*COVID-19 Drug Treatment[MESH]
  • |Amides/pharmacology/*therapeutic use[MESH]
  • |Antiviral Agents/pharmacology/*therapeutic use[MESH]
  • |COVID-19/virology[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus RNA-Dependent RNA Polymerase/*antagonists & inhibitors[MESH]
  • |Humans[MESH]
  • |Mutagenesis/drug effects[MESH]
  • |Pyrazines/pharmacology/*therapeutic use[MESH]
  • |RNA, Viral/drug effects/genetics[MESH]
  • |SARS-CoV-2/*drug effects/enzymology/genetics[MESH]


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