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10.3855/jidc.13340

http://scihub22266oqcxt.onion/10.3855/jidc.13340
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33175707!ä!33175707

suck abstract from ncbi


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pmid33175707      J+Infect+Dev+Ctries 2020 ; 14 (10): 1128-1135
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  • Demystifying the varying case fatality rates (CFR) of COVID-19 in India: Lessons learned and future directions #MMPMID33175707
  • Asirvatham ES; Lakshmanan J; Sarman CJ; Joy M
  • J Infect Dev Ctries 2020[Oct]; 14 (10): 1128-1135 PMID33175707show ga
  • INTRODUCTION: At the end of the second week of June 2020, the SARS-CoV-2 responsible for COVID-19 infected above 7.5 million people and killed over 400,000 worldwide. Estimation of case fatality rate (CFR) and determining the associated factors are critical for developing targeted interventions. METHODOLOGY: The state-level adjusted case fatality rate (aCFR) was estimated by dividing the cumulative number of deaths on a given day by the cumulative number confirmed cases 8 days before, which is the average time-lag between diagnosis and death. We conducted fractional regression analysis to determine the predictors of aCFR. RESULTS: As of 13 June 2020, India reported 225 COVID-19 cases per million population (95% CI:224-226); 6.48 deaths per million population (95% CI:6.34-6.61) and an aCFR of 3.88% (95% CI:3.81-3.97) with wide variation between states. High proportion of urban population and population above 60 years were significantly associated with increased aCFR (p=0.08, p=0.05), whereas, high literacy rate and high proportion of women were associated with reduced aCFR (p<0.001, p=0.03). The higher number of cases per million population (p=0.001), prevalence of diabetes and hypertension (p=0.012), cardiovascular diseases (p=0.05), and any cancer (p<0.001) were significantly associated with increased aCFR. The performance of state health systems and proportion of public health expenditure were not associated with aCFR. CONCLUSIONS: Socio-demographic factors and burden of non-communicable diseases (NCDs) were found to be the predictors of aCFR. Focused strategies that would ensure early identification, testing and effective targeting of non-literate, elderly, urban population and people with comorbidities are critical to control the pandemic and fatalities.
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*mortality[MESH]
  • |Data Interpretation, Statistical[MESH]
  • |Humans[MESH]
  • |India/epidemiology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*mortality[MESH]
  • |Risk Factors[MESH]


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