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10.23750/abm.v91i13-S.10520

http://scihub22266oqcxt.onion/10.23750/abm.v91i13-S.10520
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33170174!8023130!33170174
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suck abstract from ncbi


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pmid33170174      Acta+Biomed 2020 ; 91 (13-S): e2020008
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  • Natural compounds as inhibitors of SARS-CoV-2 endocytosis: A promising approach against COVID-19 #MMPMID33170174
  • Kiani AK; Dhuli K; Anpilogov K; Bressan S; Dautaj A; Dundar M; Beccari T; Ergoren MC; Bertelli M
  • Acta Biomed 2020[Nov]; 91 (13-S): e2020008 PMID33170174show ga
  • BACKGROUND AND AIM: The recent COVID-19 pandemic caused by SARS-CoV-2 affected more than six million people and caused thousands of deaths. The lack of effective drugs or vaccines against SARS-CoV-2 further worsened the situation. This review is focused on the identification of molecules that may inhibit viral entry into host cells by endocytosis. METHODS: We performed the literature search for these natural compounds in the articles indexed in PubMed. RESULTS: Natural products against viral infections have been gaining importance in recent years. Specific natural compounds like phytosterols, polyphenols, flavonoids, citrus, galangal, curcuma and hydroxytyrosol are being analyzed to understand whether they could inhibit SARS-CoV-2. CONCLUSIONS: We reviewed natural compounds with potential antiviral activity against SARS-CoV-2 that could be used as a treatment for COVID-19.
  • |*Betacoronavirus[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Biological Factors/*therapeutic use[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Endocytosis/*drug effects[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]


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