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10.1016/j.xinn.2020.100061 http://scihub22266oqcxt.onion/10.1016/j.xinn.2020.100061 33169119!7609236!33169119     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Innovation+(Camb) 2020 ; 1 (3): 100061 Nephropedia Template TP {{tp|p=33169119|t=2020. Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection |pdf=|usr=}}{{33169119}} gab.com Text Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection JO: Innovation (Camb) http://www.kidney.de/pget.php?&tw=1&pmid=33169119 #FOAvip The worldwide epidemic of coronavirus disease 2019 (COVID-19) is ongoing. Rapid and accurate detection of the causative virus SARS-CoV-2 is vital for the treatment and control of COVID-19. In this study, the comparative sensitivity of different respiratory specimen types were retrospectively analyzed using 3,552 clinical samples from 410 COVID-19 patients confirmed by Guangdong CDC (Center for Disease Control and Prevention). Except for bronchoalveolar lavage fluid (BALF), the sputum possessed the highest positive rate (73.4%-87.5%), followed by nasal swabs (53.1%-85.3%) for both severe and mild cases during the first 14 days after illness onset (d.a.o.). Viral RNA could be detected in all BALF samples collected from the severe group within 14 d.a.o. and lasted up to 46 d.a.o. Moreover, although viral RNA was negative in the upper respiratory samples, it was also positive in BALF samples in most cases from the severe group during treatment. Notably, no viral RNA was detected in BALF samples from the mild group. Despite typical ground-glass opacity observed via computed tomographic scans, no viral RNA was detected in the first three or all upper respiratory tract specimens from some COVID-19 patients. In conclusion, sputum is most sensitive for routine laboratory diagnosis of COVID-19, followed by nasal swabs. Detection of viral RNA in BALF improves diagnostic accuracy in severe COVID-19 patients. Twit Text FOAVip Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection ????Innovation (Camb) http://www.kidney.de/pget.php?&tw=1&pmid=33169119 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33169119 #FOAvip English Wikipedia <ref>{{Cite pmid|33169119}}</ref> Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection #MMPMID33169119 Yang Y; Yang M; Yuan J; Wang F; Wang Z; Li J; Zhang M; Xing L; Wei J; Peng L; Wong G; Zheng H; Wu W; Shen C; Liao M; Feng K; Li J; Yang Q; Zhao J; Liu L; Liu Y Innovation (Camb) 2020[Nov]; 1 (3): 100061 PMID33169119show ga The worldwide epidemic of coronavirus disease 2019 (COVID-19) is ongoing. Rapid and accurate detection of the causative virus SARS-CoV-2 is vital for the treatment and control of COVID-19. In this study, the comparative sensitivity of different respiratory specimen types were retrospectively analyzed using 3,552 clinical samples from 410 COVID-19 patients confirmed by Guangdong CDC (Center for Disease Control and Prevention). Except for bronchoalveolar lavage fluid (BALF), the sputum possessed the highest positive rate (73.4%-87.5%), followed by nasal swabs (53.1%-85.3%) for both severe and mild cases during the first 14 days after illness onset (d.a.o.). Viral RNA could be detected in all BALF samples collected from the severe group within 14 d.a.o. and lasted up to 46 d.a.o. Moreover, although viral RNA was negative in the upper respiratory samples, it was also positive in BALF samples in most cases from the severe group during treatment. Notably, no viral RNA was detected in BALF samples from the mild group. Despite typical ground-glass opacity observed via computed tomographic scans, no viral RNA was detected in the first three or all upper respiratory tract specimens from some COVID-19 patients. In conclusion, sputum is most sensitive for routine laboratory diagnosis of COVID-19, followed by nasal swabs. Detection of viral RNA in BALF improves diagnostic accuracy in severe COVID-19 patients. äLaboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 I(epmc).pdf DeepDyve Pubget Overpricing