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10.1177/0748730420967768 http://scihub22266oqcxt.onion/10.1177/0748730420967768 33161818!7924106!33161818     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33161818.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Biol+Rhythms 2021 ; 36 (1): 9-22 Nephropedia Template TP {{tp|p=33161818|t=2021. The Circadian Clock and Viral Infections |pdf=|usr=}}{{33161818}} gab.com Text The Circadian Clock and Viral Infections JO: J Biol Rhythms http://www.kidney.de/pget.php?&tw=1&pmid=33161818 #FOAvip The circadian clock controls several aspects of mammalian physiology and orchestrates the daily oscillations of biological processes and behavior. Our circadian rhythms are driven by an endogenous central clock in the brain that synchronizes with clocks in peripheral tissues, thereby regulating our immune system and the severity of infections. These rhythms affect the pharmacokinetics and efficacy of therapeutic agents and vaccines. The core circadian regulatory circuits and clock-regulated host pathways provide fertile ground to identify novel antiviral therapies. An increased understanding of the role circadian systems play in regulating virus infection and the host response to the virus will inform our clinical management of these diseases. This review provides an overview of the experimental and clinical evidence reporting on the interplay between the circadian clock and viral infections, highlighting the importance of virus-clock research. Twit Text FOAVip The Circadian Clock and Viral Infections ????J Biol Rhythms http://www.kidney.de/pget.php?&tw=1&pmid=33161818 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33161818 #FOAvip English Wikipedia <ref>{{Cite pmid|33161818}}</ref> The Circadian Clock and Viral Infections #MMPMID33161818 Borrmann H; McKeating JA; Zhuang X J Biol Rhythms 2021[Feb]; 36 (1): 9-22 PMID33161818show ga The circadian clock controls several aspects of mammalian physiology and orchestrates the daily oscillations of biological processes and behavior. Our circadian rhythms are driven by an endogenous central clock in the brain that synchronizes with clocks in peripheral tissues, thereby regulating our immune system and the severity of infections. These rhythms affect the pharmacokinetics and efficacy of therapeutic agents and vaccines. The core circadian regulatory circuits and clock-regulated host pathways provide fertile ground to identify novel antiviral therapies. An increased understanding of the role circadian systems play in regulating virus infection and the host response to the virus will inform our clinical management of these diseases. This review provides an overview of the experimental and clinical evidence reporting on the interplay between the circadian clock and viral infections, highlighting the importance of virus-clock research. |Animals[MESH] |CLOCK Proteins/*genetics/metabolism[MESH] |Circadian Clocks/*physiology[MESH] |Circadian Rhythm/*physiology[MESH] |Gene Expression[MESH] |Host-Pathogen Interactions/genetics[MESH] |Humans[MESH] |Virus Diseases/*genetics/metabolism/virology[MESH] |Virus Replication/genetics[MESH]The Circadian Clock and Viral Infections (epmc).pdf DeepDyve Pubget Overpricing