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10.1016/j.dsx.2020.10.022

http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.10.022
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33161221!7598371!33161221
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suck abstract from ncbi


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pmid33161221      Diabetes+Metab+Syndr 2020 ; 14 (6): 2103-2109
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  • Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis #MMPMID33161221
  • Tuty Kuswardhani RA; Henrina J; Pranata R; Anthonius Lim M; Lawrensia S; Suastika K
  • Diabetes Metab Syndr 2020[Nov]; 14 (6): 2103-2109 PMID33161221show ga
  • BACKGROUND AND AIMS: The ongoing COVID-19 pandemic is disproportionately affecting patients with comorbidities. Therefore, thorough comorbidities assessment can help establish risk stratification of patients with COVID-19, upon hospital admission. Charlson Comorbidity Index (CCI) is a validated, simple, and readily applicable method of estimating the risk of death from comorbid disease and has been widely used as a predictor of long-term prognosis and survival. METHODS: We performed a systematic review and meta-analysis of CCI score and a composite of poor outcomes through several databases. RESULTS: Compared to a CCI score of 0, a CCI score of 1-2 and CCI score of >/=3 was prognostically associated with mortality and associated with a composite of poor outcomes. Per point increase of CCI score also increased mortality risk by 16%. Moreover, a higher mean CCI score also significantly associated with mortality and disease severity. CONCLUSION: CCI score should be utilized for risk stratifications of hospitalized COVID-19 patients.
  • |COVID-19/diagnosis/*mortality/*therapy[MESH]
  • |Comorbidity/trends[MESH]
  • |Hospitalization/*trends[MESH]
  • |Humans[MESH]
  • |Prospective Studies[MESH]
  • |Retrospective Studies[MESH]


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