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10.1016/j.jcv.2020.104659

http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104659
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33160179!7561603!33160179
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suck abstract from ncbi


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pmid33160179      J+Clin+Virol 2020 ; 133 (ä): 104659
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  • Panbio antigen rapid test is reliable to diagnose SARS-CoV-2 infection in the first 7 days after the onset of symptoms #MMPMID33160179
  • Linares M; Perez-Tanoira R; Carrero A; Romanyk J; Perez-Garcia F; Gomez-Herruz P; Arroyo T; Cuadros J
  • J Clin Virol 2020[Dec]; 133 (ä): 104659 PMID33160179show ga
  • BACKGROUND: RT-qPCR is the current recommended laboratory method to diagnose SARS-CoV-2 acute infection, several factors such as requirement of special equipment, time consuming, high cost and skilled staff limit the use of these techniques. A more rapid and high-throughput method is essential. METHODS: We analyzed clinical data and nasopharyngeal samples, collected during September 2020, from patients attended at the emergency department of a secondary hospital and in two primary healthcare centers in Madrid. The performance of the Panbio COVID-19 AG Rapid Test Device for the detection of SARS-CoV-2 antigen was compared to RT-qPCR. RESULTS: 255 nasopharyngeal swabs, including 150 from the emergency department and 105 from primary helthcare centers, were tested. 184 patients were symptomatic (72.1 %). Amongst the 60 positive RT-qPCR samples, 40 were detected by the rapid antigen test, given an overall sensitivity of 73.3 %. All the samples detected positive with the rapid antigen test were also positive with RT-qPCR. The median cycle threshold was 23.28 (IQR 18.5-30.16). Patients with less than seven days onset of symptoms showed a higher viral load, and sensitivity for rapid antigen test (86.5 %), compared to those with more days (sensitivity of 53.8 %)(p?
  • |Adult[MESH]
  • |Aged[MESH]
  • |Antigens, Viral/*analysis[MESH]
  • |COVID-19 Testing/*methods[MESH]
  • |COVID-19/*diagnosis/immunology[MESH]
  • |Early Diagnosis[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoassay[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/virology[MESH]
  • |Point-of-Care Testing[MESH]
  • |Reagent Kits, Diagnostic[MESH]
  • |Sensitivity and Specificity[MESH]


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