Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.ijid.2020.10.100 http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.10.100 33160064!7641537!33160064     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33160064&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Int+J+Infect+Dis 2021 ; 102 (?): 566-570 Nephropedia Template TP {{tp|p=33160064|t=2021. Arginine depletion as a therapeutic approach for patients with COVID-19 |pdf=|usr=}}{{33160064}} gab.com Text Arginine depletion as a therapeutic approach for patients with COVID-19 JO: Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33160064 #FOAvip The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a source of significant morbidity and death worldwide, and effective treatments are urgently needed. Clinical trials have focused largely on direct antiviral therapies or on immunomodulation in patients with severe manifestations of COVID-19. One therapeutic approach that remains to be clinically investigated is disruption of the host-virus relationship through amino acid restriction, a strategy used successfully in the setting of cancer treatment. Arginine is an amino acid that has been shown in nonclinical studies to be essential in the life cycle of many viruses. Therefore, arginine depletion may be an effective therapeutic approach against SARS-CoV-2. Several arginine-metabolizing enzymes in clinical development may be a viable approach to induce a low arginine environment to treat COVID-19 and other viral diseases. Herein, we explore the rationale for arginine depletion as a therapeutic approach for COVID-19. Twit Text FOAVip Arginine depletion as a therapeutic approach for patients with COVID-19 ????Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33160064 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33160064 #FOAvip English Wikipedia <ref>{{Cite pmid|33160064}}</ref> Arginine depletion as a therapeutic approach for patients with COVID-19 #MMPMID33160064 Grimes JM; Khan S; Badeaux M; Rao RM; Rowlinson SW; Carvajal RD Int J Infect Dis 2021[Jan]; 102 (?): 566-570 PMID33160064show ga The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a source of significant morbidity and death worldwide, and effective treatments are urgently needed. Clinical trials have focused largely on direct antiviral therapies or on immunomodulation in patients with severe manifestations of COVID-19. One therapeutic approach that remains to be clinically investigated is disruption of the host-virus relationship through amino acid restriction, a strategy used successfully in the setting of cancer treatment. Arginine is an amino acid that has been shown in nonclinical studies to be essential in the life cycle of many viruses. Therefore, arginine depletion may be an effective therapeutic approach against SARS-CoV-2. Several arginine-metabolizing enzymes in clinical development may be a viable approach to induce a low arginine environment to treat COVID-19 and other viral diseases. Herein, we explore the rationale for arginine depletion as a therapeutic approach for COVID-19. |Animals[MESH] |Arginine/*deficiency[MESH] |COVID-19/*metabolism/*therapy/virology[MESH] |Humans[MESH]Arginine depletion as a therapeutic approach for patients with COVID-1(epmc).pdf DeepDyve Pubget Overpricing