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10.1016/j.jri.2020.103243

http://scihub22266oqcxt.onion/10.1016/j.jri.2020.103243
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33157499!7598537!33157499
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suck abstract from ncbi


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pmid33157499      J+Reprod+Immunol 2021 ; 143 (ä): 103243
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  • Detailed immune monitoring of a pregnant woman with critical Covid-19 #MMPMID33157499
  • du Fosse NA; Bronsgeest K; Arbous MS; Zlei M; Myeni SK; Kikkert M; van Dongen J; Staal F; van der Hoorn M; van den Akker T
  • J Reprod Immunol 2021[Feb]; 143 (ä): 103243 PMID33157499show ga
  • A primigravid woman with Covid-19 related respiratory insufficiency was admitted into a tertiary Intensive Care Unit at 23 3/7 weeks' gestation. Highly sensitive flow cytometry of peripheral leukocytes indicated significantly suppressed naive T- and B-cell compartments. The suppressed immune cell responses led us keep the initially started administration of corticosteroids for fetal and maternal indication at a low dose. After three weeks her B-cell response peaked, SARS-CoV-2 was cleared and clinical improvement ensued a week later. At 28 weeks' gestation, a son of 1570 g was born by cesarean section. She was extubated two days postpartum and discharged from hospital 5.5 weeks postpartum.
  • |Adult[MESH]
  • |B-Lymphocytes/*immunology[MESH]
  • |COVID-19/*diagnosis/immunology[MESH]
  • |Cesarean Section[MESH]
  • |Critical Care[MESH]
  • |Female[MESH]
  • |Flow Cytometry[MESH]
  • |Gravidity[MESH]
  • |Humans[MESH]
  • |Immunosuppression Therapy[MESH]
  • |Pregnancy Complications, Infectious/*diagnosis[MESH]
  • |Pregnancy/*immunology[MESH]
  • |Respiratory Insufficiency/*diagnosis[MESH]
  • |SARS-CoV-2/*physiology[MESH]


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