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10.1097/DAD.0000000000001829 http://scihub22266oqcxt.onion/10.1097/DAD.0000000000001829 33156022!ä!33156022 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33156022&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Dermatopathol 2021 ; 43 (4): e47-e50 Nephropedia Template TP {{tp|p=33156022|t=2021. COVID Purpura (Toes) Case Series: A Chilblains-Like Vasculopathy |pdf=|usr=}}{{33156022}} gab.com Text COVID Purpura (Toes) Case Series: A Chilblains-Like Vasculopathy JO: Am J Dermatopathol http://www.kidney.de/pget.php?&tw=1&pmid=33156022 #FOAvip Biopsies were taken from 4 patients who presented to their dermatologist with violaceous papules and plaques of the dorsal toes (COVID Toes) associated with varying degrees of severe acute respiratory syndrome coronavirus 2 exposure and COVID-19 testing. Major histopathologic findings were lymphocytic eccrine inflammation and a spectrum of vasculopathic findings to include superficial and deep angiocentric-perivascular lymphocytic inflammation, lymphocytes in vessel walls (lymphocytic vasculitis), endothelial swelling, red blood cell extravasation, and focal deposits of fibrin in both vessel lumina, and vessel walls. Interface changes were observed to include vacuolopathy and apoptotic keratinocytes at the basement membrane. Immunostains showed a dominant T-cell lineage (positive for T-cell receptor beta, CD2, CD3, CD5, and CD7). B-cells were rare and clusters of CD123-positive dermal plasmacytoid dendritic cells were observed surrounding eccrine clusters and some perivascular zones. The consistent perieccrine and vasculopathic features represent important pathologic findings in the diagnosis of COVID toes and are suggestive of pathogenetic mechanisms. Clinicopathologic correlation, the epidemiological backdrop, and the current worldwide COVID-19 pandemic favor a viral causation and should alert the physician to initiate a workup and the appropriate use of COVID-19 testing. Twit Text FOAVip COVID Purpura (Toes) Case Series: A Chilblains-Like Vasculopathy ????Am J Dermatopathol http://www.kidney.de/pget.php?&tw=1&pmid=33156022 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33156022 #FOAvip English Wikipedia <ref>{{Cite pmid|33156022}}</ref> COVID Purpura (Toes) Case Series: A Chilblains-Like Vasculopathy #MMPMID33156022 Olsen TG; Shrit MA; Feeser TA; Wargo JJ Am J Dermatopathol 2021[Apr]; 43 (4): e47-e50 PMID33156022show ga Biopsies were taken from 4 patients who presented to their dermatologist with violaceous papules and plaques of the dorsal toes (COVID Toes) associated with varying degrees of severe acute respiratory syndrome coronavirus 2 exposure and COVID-19 testing. Major histopathologic findings were lymphocytic eccrine inflammation and a spectrum of vasculopathic findings to include superficial and deep angiocentric-perivascular lymphocytic inflammation, lymphocytes in vessel walls (lymphocytic vasculitis), endothelial swelling, red blood cell extravasation, and focal deposits of fibrin in both vessel lumina, and vessel walls. Interface changes were observed to include vacuolopathy and apoptotic keratinocytes at the basement membrane. Immunostains showed a dominant T-cell lineage (positive for T-cell receptor beta, CD2, CD3, CD5, and CD7). B-cells were rare and clusters of CD123-positive dermal plasmacytoid dendritic cells were observed surrounding eccrine clusters and some perivascular zones. The consistent perieccrine and vasculopathic features represent important pathologic findings in the diagnosis of COVID toes and are suggestive of pathogenetic mechanisms. Clinicopathologic correlation, the epidemiological backdrop, and the current worldwide COVID-19 pandemic favor a viral causation and should alert the physician to initiate a workup and the appropriate use of COVID-19 testing. |Adult[MESH] |COVID-19/*complications/*pathology[MESH] |Chilblains/pathology/*virology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Purpura/pathology/*virology[MESH] |SARS-CoV-2[MESH] |Toes/*pathology[MESH] |Vascular Diseases/pathology/*virology[MESH]COVID Purpura (Toes) Case Series: A Chilblains-Like Vasculopathy (epmc).pdf DeepDyve Pubget Overpricing