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10.1111/tbed.13914 http://scihub22266oqcxt.onion/10.1111/tbed.13914 33155439!ä!33155439 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Transbound+Emerg+Dis 2021 ; 68 (4): 2465-2476 Nephropedia Template TP {{tp|p=33155439|t=2021. Several lineages of porcine epidemic diarrhea virus in Colombia during the 2014 and 2016 epidemic |pdf=|usr=}}{{33155439}} gab.com Text Several lineages of porcine epidemic diarrhea virus in Colombia during the 2014 and 2016 epidemic JO: Transbound Emerg Dis http://www.kidney.de/pget.php?&tw=1&pmid=33155439 #FOAvip Porcine epidemic diarrhea virus (PEDV) is a significant global, enteric coronavirus in pigs and was first reported in Colombia in 2014. However, the epidemiology, genetic and antigenic characteristics of the virus have yet to be investigated. In this study, we investigated the dissemination of PEDV by testing 536 samples by RT-PCR over a 33-month period. The 35.8% of positive samples (n = 192) was significantly different (p < .01) between months over time, with a higher number of positives samples occurring at the beginning of the epidemic and during the second epidemic wave within the main pork producing region. The complete PEDV genomes were generated for 21 strains, which shared a high nucleotide and amino acid sequence identity, except for the spike (S) gene. Recombinant regions were identified within the Colombian strains and between Colombian and Asian PEDV strains. Phylogenetic analysis of the 21 Colombian strains demonstrated the presence of 7 lineages that shared common ancestors with PEDV strains from the United States. Moreover, the antigenic analysis demonstrated residue differences in the neutralizing epitopes in the spike and nucleocapsid proteins. Our results illustrated the simultaneous introduction of the two PEDV genotypes (GIIa American pandemic and S-INDEL) into the Colombian swine industry during the 2014 PEDV epidemic and enhanced our understanding of the epidemiology and molecular diversity of PEDV in Colombia. Twit Text FOAVip Several lineages of porcine epidemic diarrhea virus in Colombia during the 2014 and 2016 epidemic ????Transbound Emerg Dis http://www.kidney.de/pget.php?&tw=1&pmid=33155439 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33155439 #FOAvip English Wikipedia <ref>{{Cite pmid|33155439}}</ref> Several lineages of porcine epidemic diarrhea virus in Colombia during the 2014 and 2016 epidemic #MMPMID33155439 Qi M; Zambrano-Moreno C; Pineda P; Calderon C; Rincon-Monroy MA; Diaz A; Marthaler DG Transbound Emerg Dis 2021[Jul]; 68 (4): 2465-2476 PMID33155439show ga Porcine epidemic diarrhea virus (PEDV) is a significant global, enteric coronavirus in pigs and was first reported in Colombia in 2014. However, the epidemiology, genetic and antigenic characteristics of the virus have yet to be investigated. In this study, we investigated the dissemination of PEDV by testing 536 samples by RT-PCR over a 33-month period. The 35.8% of positive samples (n = 192) was significantly different (p < .01) between months over time, with a higher number of positives samples occurring at the beginning of the epidemic and during the second epidemic wave within the main pork producing region. The complete PEDV genomes were generated for 21 strains, which shared a high nucleotide and amino acid sequence identity, except for the spike (S) gene. Recombinant regions were identified within the Colombian strains and between Colombian and Asian PEDV strains. Phylogenetic analysis of the 21 Colombian strains demonstrated the presence of 7 lineages that shared common ancestors with PEDV strains from the United States. Moreover, the antigenic analysis demonstrated residue differences in the neutralizing epitopes in the spike and nucleocapsid proteins. Our results illustrated the simultaneous introduction of the two PEDV genotypes (GIIa American pandemic and S-INDEL) into the Colombian swine industry during the 2014 PEDV epidemic and enhanced our understanding of the epidemiology and molecular diversity of PEDV in Colombia. |*Coronavirus Infections/epidemiology/veterinary[MESH] |*Porcine epidemic diarrhea virus/genetics[MESH] |*Swine Diseases/epidemiology[MESH] |Animals[MESH] |Colombia/epidemiology[MESH] |Epidemics/veterinary[MESH] |Phylogeny[MESH] |Swine[MESH]Several lineages of porcine epidemic diarrhea virus in Colombia during(epmc).pdf DeepDyve Pubget Overpricing