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10.1183/16000617.0199-2020

http://scihub22266oqcxt.onion/10.1183/16000617.0199-2020
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33153991!7651840!33153991
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suck abstract from ncbi


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pmid33153991      Eur+Respir+Rev 2020 ; 29 (158): ä
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  • COVID-19 and COPD: a narrative review of the basic science and clinical outcomes #MMPMID33153991
  • Higham A; Mathioudakis A; Vestbo J; Singh D
  • Eur Respir Rev 2020[Dec]; 29 (158): ä PMID33153991show ga
  • The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in males, older individuals and patients with comorbidities. COPD patients are included in shielding strategies due to their susceptibility to virus-induced exacerbations, compromised pulmonary function and high prevalence of associated comorbidities. Using evidence from basic science and cohort studies, this review addresses key questions concerning COVID-19 and COPD. First, are there mechanisms by which COPD patients are more susceptible to SARS-CoV-2 infection? Secondly, do inhaled corticosteroids offer protection against COVID-19? And, thirdly, what is the evidence regarding clinical outcomes from COVID-19 in COPD patients? This up-to-date review tackles some of the key issues which have significant impact on the long-term outlook for COPD patients in the context of COVID-19.
  • |*Disease Progression[MESH]
  • |*Disease Susceptibility[MESH]
  • |Adult[MESH]
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*diagnosis/*epidemiology/therapy[MESH]
  • |Evidence-Based Medicine[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Middle Aged[MESH]
  • |Pandemics/statistics & numerical data[MESH]
  • |Pneumonia, Viral/*diagnosis/*epidemiology/therapy[MESH]
  • |Prognosis[MESH]
  • |Pulmonary Disease, Chronic Obstructive/*diagnosis/*epidemiology/therapy[MESH]
  • |Respiratory Function Tests[MESH]
  • |Risk Assessment[MESH]
  • |Severe Acute Respiratory Syndrome/diagnosis/epidemiology[MESH]
  • |Severity of Illness Index[MESH]


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