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Early outcomes of Stanford type A aortic dissection under the coronavirus disease 2019 (COVID-19) pandemic: a multicentre study from Hubei province #MMPMID33150432
Hu X; Wang Y; Liu J; Qiu X; Liu X; Jiang X; Huang X; Feng X; Zhang Y; Zhang S; Qian H; Liu W; Zhang J; Dong J; Chen J; Xia J; Dong N; Wu L
Interact Cardiovasc Thorac Surg 2020[Dec]; 31 (6): 834-840 PMID33150432show ga
OBJECTIVES: Our goal was to compare the short-term outcomes of Stanford type A aortic dissection (TAAD), during the coronavirus disease 2019 (COVID-19) pandemic with those during normal times and summarize our perioperative management experience of patients with TAAD in the context of COVID-19. METHODS: From 17 January 2020 to 8 March 2020, a total of 27 patients with TAAD were operated on in 8 cardiovascular surgery centres in Hubei Province (COVID-19 group). The data from 91 patients with TAAD from the same centres during the same period last year were extracted from the Hubei Cardiac Surgery Registration System (control group). A propensity score matched subgroup of 26 pairs (1:2) was identified. Perioperative data and short-term outcomes were assessed. RESULTS: Nine patients in the COVID-19 group were categorized as suspicious for the disease (9/27, 33.3%), and others were excluded (18/27, 66.7%). No one was laboratory confirmed preoperatively. The average waiting, cross-clamp and circulatory arrest times were longer in the COVID-19 group (22.9 +/- 8.3 vs 9.7 +/- 4.0 h, P < 0.001; 135 +/- 36 vs 103 +/- 45 min, P = 0.003; 24 +/- 9 vs 17 +/- 8 min, P < 0.001, respectively). The 30-day or in-hospital deaths were 3.8% in both groups (P = 1.0). The COVID-19 group was associated with longer ventilation and intensive care unit times (81 +/- 71 vs 45 +/- 19 h, P < 0.001; 7.4 +/- 3.8 vs 4.5 +/- 2.7 days; P < 0.001, respectively). There were no statistical differences between the 2 groups in the incidence of complications such as stroke, neurological deficit, acute kidney injury, pulmonary infection and reoperation. Serum antibody tests for those patients showed 7 out of 9 suspected cases were Immunoglobulin G positive. No cross-infection occurred in other patients or associated medical staff. CONCLUSIONS: With adequate preparation and appropriate protection, satisfactory early outcomes can be achieved after emergency operations for patients with TAAD during the COVID-19 pandemic.
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Interact+Cardiovasc+Thorac+Surg 2020 ; 31 (6): 834-840
