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10.1142/S0192415X20500755

http://scihub22266oqcxt.onion/10.1142/S0192415X20500755
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33148005!?!33148005

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suck abstract from ncbi

pmid33148005      Am+J+Chin+Med 2020 ; 48 (7): 1523-1538
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  • Traditional Chinese Medicine Formulation Therapy in the Treatment of Coronavirus Disease 2019 (COVID-19) #MMPMID33148005
  • Shi J; Lu Y; Zhang Y; Xia L; Ye C; Lu Y; Chen S; Xu Q; Tang B; Yin K; Zhang J; Chen X; Yang Z
  • Am J Chin Med 2020[]; 48 (7): 1523-1538 PMID33148005show ga
  • This study aimed to investigate the efficacy of Traditional Chinese Medicine (TCM) decoction with different intervention timepoints in the treatment of coronavirus disease 2019 (COVID-19) patients. We retrospectively collected the medical records and evaluated the outcomes of COVID-19 patients that received TCM decoction treatment at different timepoints. A total of 234 COVID-19 patients were included in this study. Patients who received TCM decoction therapy within 3 days or 7 days after admission could achieve shorter hospitalization days and disease periods compared to those who received TCM decoction [Formula: see text] 7 days after admission (all [Formula: see text]). Patients who received TCM decoction therapy within 3 days had significantly fewer days to negative SARS-CoV-2 from nasopharyngeal/oral swab and days to negative SARS-CoV-2 from urine/stool/blood samples compared to those received TCM decoction [Formula: see text] days after admission (all [Formula: see text]). Patients who received TCM decoction therapy on the 3rd to 7th day after admission had a faster achievement of negative SARS-CoV-2 from urine/stool/blood samples compared to those who received TCM decoction [Formula: see text] days after admission ([Formula: see text]). Logistic models revealed that more days from TCM decoction to admission [Formula: see text] days might be a risk factor for long hospitalization days, disease period, and slower negative-conversion of SARS-CoV-2 (all [Formula: see text]). Conclusively, our results suggest that TCM decoction therapy should be considered at the early stage of COVID-19 patients.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/epidemiology/virology[MESH]
  • |Drugs, Chinese Herbal/*therapeutic use[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Length of Stay/statistics & numerical data[MESH]
  • |Male[MESH]
  • |Medicine, Chinese Traditional/*methods[MESH]
  • |Middle Aged[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/*drug effects/physiology[MESH]


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