Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/biom10111505 http://scihub22266oqcxt.onion/10.3390/biom10111505 33147723!7693102!33147723     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomolecules 2020 ; 10 (11): ä Nephropedia Template TP {{tp|p=33147723|t=2020. Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid |pdf=|usr=}}{{33147723}} gab.com Text Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid JO: Biomolecules http://www.kidney.de/pget.php?&tw=1&pmid=33147723 #FOAvip Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential of UNA with a comparison to ursolic acid (ULA), a well-known secondary metabolite, for beneficial effects. UNA has a keto group at the C-3 position, which may provide a critical difference for the varied biological activities between UNA and ULA. Several studies previously showed that UNA exerts pharmaceutical effects similar to, or stronger than, ULA, with UNA significantly decreasing the survival and proliferation of various types of cancer cells. UNA has potential to exert inhibitory effects in parasitic protozoa that cause several tropical diseases. UNA also exerts other potential effects, including antihyperglycemic, anti-inflammatory, antiviral, and antioxidant activities. Of note, a recent study highlighted the suppressive potential of UNA against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molecular modifications of UNA may enhance bioavailability, which is crucial for in vivo and clinical studies. In conclusion, UNA has promising potential to be developed in anticancer and antiprotozoan pharmaceuticals. In-depth investigations may increase the possibility of UNA being developed as a novel reagent for chemotherapy. Twit Text FOAVip Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid ????Biomolecules http://www.kidney.de/pget.php?&tw=1&pmid=33147723 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33147723 #FOAvip English Wikipedia <ref>{{Cite pmid|33147723}}</ref> Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid #MMPMID33147723 Son J; Lee SY Biomolecules 2020[Nov]; 10 (11): ä PMID33147723show ga Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential of UNA with a comparison to ursolic acid (ULA), a well-known secondary metabolite, for beneficial effects. UNA has a keto group at the C-3 position, which may provide a critical difference for the varied biological activities between UNA and ULA. Several studies previously showed that UNA exerts pharmaceutical effects similar to, or stronger than, ULA, with UNA significantly decreasing the survival and proliferation of various types of cancer cells. UNA has potential to exert inhibitory effects in parasitic protozoa that cause several tropical diseases. UNA also exerts other potential effects, including antihyperglycemic, anti-inflammatory, antiviral, and antioxidant activities. Of note, a recent study highlighted the suppressive potential of UNA against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molecular modifications of UNA may enhance bioavailability, which is crucial for in vivo and clinical studies. In conclusion, UNA has promising potential to be developed in anticancer and antiprotozoan pharmaceuticals. In-depth investigations may increase the possibility of UNA being developed as a novel reagent for chemotherapy. |Animals[MESH] |Anti-Inflammatory Agents, Non-Steroidal/chemistry/pharmacology[MESH] |Antineoplastic Agents, Phytogenic/pharmacology[MESH] |Antioxidants/chemistry/pharmacology[MESH] |Antiprotozoal Agents/chemistry/pharmacology[MESH] |Antiviral Agents/chemistry/*pharmacology[MESH] |Betacoronavirus/drug effects/physiology[MESH] |Humans[MESH] |Hypoglycemic Agents/chemistry/pharmacology[MESH] |Plants/chemistry[MESH] |SARS-CoV-2[MESH] |Triterpenes/chemistry/metabolism/*pharmacology[MESH]Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid (epmc).pdf DeepDyve Pubget Overpricing