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10.1590/0001-3765202020201208 http://scihub22266oqcxt.onion/10.1590/0001-3765202020201208 33146237!ä!33146237 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33146237&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       An+Acad+Bras+Cienc 2020 ; 92 (4): e20201208 Nephropedia Template TP {{tp|p=33146237|t=2020. Problems of Interpreting Diagnostic Tests for SARS-CoV-2: Analytical Chemistry Concerns |pdf=|usr=}}{{33146237}} gab.com Text Problems of Interpreting Diagnostic Tests for SARS-CoV-2: Analytical Chemistry Concerns JO: An Acad Bras Cienc http://www.kidney.de/pget.php?&tw=1&pmid=33146237 #FOAvip The COVID-19 pandemic outbreak made the development of reliable, sensitive, and reproducible testing methods crucial throughout the world. Without proper analytical validation, testing results can be misinterpreted, leading to a certain degree of misinformation in the clinical area. To accurately assess the methods, the determination of an analytical linear range of response of the assay is fundamental. Based on this curve, the evaluation of some parameters as sensitivity, limit of detection, and limit of quantification can be done, as well as the establishment of cut-off values. Statistical treatments of the collected data can be performed for reproducibility and reliability evaluations. In this context, there is a wide range of analytical concerns that should be in-depth discussed in medical, biomedical and chemical areas. This letter aims to briefly clarify some analytical chemistry concepts, as sensitivity, cut-off and limit of detection, and their application towards clinical diagnosis. Twit Text FOAVip Problems of Interpreting Diagnostic Tests for SARS-CoV-2: Analytical Chemistry Concerns ????An Acad Bras Cienc http://www.kidney.de/pget.php?&tw=1&pmid=33146237 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33146237 #FOAvip English Wikipedia <ref>{{Cite pmid|33146237}}</ref> Problems of Interpreting Diagnostic Tests for SARS-CoV-2: Analytical Chemistry Concerns #MMPMID33146237 Mattioli IA; Crespilho FN An Acad Bras Cienc 2020[]; 92 (4): e20201208 PMID33146237show ga The COVID-19 pandemic outbreak made the development of reliable, sensitive, and reproducible testing methods crucial throughout the world. Without proper analytical validation, testing results can be misinterpreted, leading to a certain degree of misinformation in the clinical area. To accurately assess the methods, the determination of an analytical linear range of response of the assay is fundamental. Based on this curve, the evaluation of some parameters as sensitivity, limit of detection, and limit of quantification can be done, as well as the establishment of cut-off values. Statistical treatments of the collected data can be performed for reproducibility and reliability evaluations. In this context, there is a wide range of analytical concerns that should be in-depth discussed in medical, biomedical and chemical areas. This letter aims to briefly clarify some analytical chemistry concepts, as sensitivity, cut-off and limit of detection, and their application towards clinical diagnosis. |*Coronavirus Infections/diagnosis[MESH] |*Diagnostic Tests, Routine[MESH] |*Pandemics[MESH] |*Pneumonia, Viral[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Clinical Laboratory Techniques[MESH] |Humans[MESH] |Reproducibility of Results[MESH] |SARS-CoV-2[MESH]Problems of Interpreting Diagnostic Tests for SARS-CoV-2: Analytical C(epmc).pdf DeepDyve Pubget Overpricing