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10.1002/art.41567

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33146001!8467766!33146001
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suck abstract from ncbi


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pmid33146001      Arthritis+Rheumatol 2021 ; 73 (3): 374-380
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  • Association of Race and Ethnicity With COVID-19 Outcomes in Rheumatic Disease: Data From the COVID-19 Global Rheumatology Alliance Physician Registry #MMPMID33146001
  • Gianfrancesco MA; Leykina LA; Izadi Z; Taylor T; Sparks JA; Harrison C; Trupin L; Rush S; Schmajuk G; Katz P; Jacobsohn L; Hsu TY; D'Silva KM; Serling-Boyd N; Wallwork R; Todd DJ; Bhana S; Costello W; Grainger R; Hausmann JS; Liew JW; Sirotich E; Sufka P; Wallace ZS; Machado PM; Robinson PC; Yazdany J
  • Arthritis Rheumatol 2021[Mar]; 73 (3): 374-380 PMID33146001show ga
  • OBJECTIVE: Racial/ethnic minorities experience more severe outcomes of coronavirus disease 2019 (COVID-19) in the general US population. This study was undertaken to examine the association between race/ethnicity and COVID-19 hospitalization, ventilation status, and mortality in people with rheumatic disease. METHODS: US patients with rheumatic disease and COVID-19 were entered into the COVID-19 Global Rheumatology Alliance physician registry between March 24, 2020 and August 26, 2020 were included. Race/ethnicity was defined as White, African American, Latinx, Asian, or other/mixed race. Outcome measures included hospitalization, requirement for ventilatory support, and death. Multivariable regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) adjusted for age, sex, smoking status, rheumatic disease diagnosis, comorbidities, medication use prior to infection, and rheumatic disease activity. RESULTS: A total of 1,324 patients were included, of whom 36% were hospitalized and 6% died; 26% of hospitalized patients required mechanical ventilation. In multivariable models, African American patients (OR 2.74 [95% CI 1.90-3.95]), Latinx patients (OR 1.71 [95% CI 1.18-2.49]), and Asian patients (OR 2.69 [95% CI 1.16-6.24]) had higher odds of hospitalization compared to White patients. Latinx patients also had 3-fold increased odds of requiring ventilatory support (OR 3.25 [95% CI 1.75-6.05]). No differences in mortality based on race/ethnicity were found, though power to detect associations may have been limited. CONCLUSION: Similar to findings in the general US population, racial/ethnic minorities with rheumatic disease and COVID-19 had increased odds of hospitalization and ventilatory support. These results illustrate significant health disparities related to COVID-19 in people with rheumatic diseases. The rheumatology community should proactively address the needs of patients currently experiencing inequitable health outcomes during the pandemic.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/complications/*ethnology/mortality[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Ethnicity/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Odds Ratio[MESH]
  • |Racial Groups/*statistics & numerical data[MESH]
  • |Registries[MESH]
  • |Respiration, Artificial/statistics & numerical data[MESH]
  • |Rheumatic Diseases/*ethnology/mortality/virology[MESH]
  • |Rheumatology/*statistics & numerical data[MESH]
  • |SARS-CoV-2[MESH]
  • |United States/epidemiology[MESH]


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