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10.3390/ijms21218176 http://scihub22266oqcxt.onion/10.3390/ijms21218176 33142933!7663479!33142933     free     free     free       Int+J+Mol+Sci 2020 ; 21 (21): ? Nephropedia Template TP {{tp|p=33142933|t=2020. The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections |pdf=|usr=}}{{33142933}} gab.com Text The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=33142933 #FOAvip Eukaryotic 5-methylcytosine RNA methyltransferases catalyze the transfer of a methyl group to the fifth carbon of a cytosine base in RNA sequences to produce 5-methylcytosine (m(5)C). m(5)C RNA methyltransferases play a crucial role in the maintenance of functionality and stability of RNA. Viruses have developed a number of strategies to suppress host innate immunity and ensure efficient transcription and translation for the replication of new virions. One such viral strategy is to use host m(5)C RNA methyltransferases to modify viral RNA and thus to affect antiviral host responses. Here, we summarize the latest findings concerning the roles of m(5)C RNA methyltransferases, namely, NOL1/NOP2/SUN domain (NSUN) proteins and DNA methyltransferase 2/tRNA methyltransferase 1 (DNMT2/TRDMT1) during viral infections. Moreover, the use of m(5)C RNA methyltransferase inhibitors as an antiviral therapy is discussed. Twit Text FOAVip The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=33142933 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33142933 #FOAvip English Wikipedia <ref>{{Cite pmid|33142933}}</ref> The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections #MMPMID33142933 Wnuk M; Slipek P; Dziedzic M; Lewinska A Int J Mol Sci 2020[Oct]; 21 (21): ? PMID33142933show ga Eukaryotic 5-methylcytosine RNA methyltransferases catalyze the transfer of a methyl group to the fifth carbon of a cytosine base in RNA sequences to produce 5-methylcytosine (m(5)C). m(5)C RNA methyltransferases play a crucial role in the maintenance of functionality and stability of RNA. Viruses have developed a number of strategies to suppress host innate immunity and ensure efficient transcription and translation for the replication of new virions. One such viral strategy is to use host m(5)C RNA methyltransferases to modify viral RNA and thus to affect antiviral host responses. Here, we summarize the latest findings concerning the roles of m(5)C RNA methyltransferases, namely, NOL1/NOP2/SUN domain (NSUN) proteins and DNA methyltransferase 2/tRNA methyltransferase 1 (DNMT2/TRDMT1) during viral infections. Moreover, the use of m(5)C RNA methyltransferase inhibitors as an antiviral therapy is discussed. |*RNA Processing, Post-Transcriptional[MESH] |5-Methylcytosine/*chemistry/metabolism[MESH] |Animals[MESH] |Humans[MESH] |Methyltransferases/genetics/*metabolism[MESH] |RNA, Viral/*metabolism[MESH]The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral(epmc).pdf DeepDyve Pubget Overpricing