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10.1080/01652176.2020.1845917 http://scihub22266oqcxt.onion/10.1080/01652176.2020.1845917 33138721!7671703!33138721     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Vet+Q 2020 ; 40 (1): 322-330 Nephropedia Template TP {{tp|p=33138721|t=2020. Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive cats |pdf=|usr=}}{{33138721}} gab.com Text Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive cats JO: Vet Q http://www.kidney.de/pget.php?&tw=1&pmid=33138721 #FOAvip Feline infectious peritonitis (FIP) is a viral-induced, immune-mediated disease of cats caused by virulent biotypes of feline coronaviruses (FCoV), known as the feline infectious peritonitis virus (FIPV). Historically, three major pharmacological approaches have been employed to treat FIP: (1) immunomodulators to stimulate the patient's immune system non-specifically to reduce the clinical effects of the virus through a robust immune response, (2) immunosuppressive agents to dampen clinical signs temporarily, and (3) re-purposed human antiviral drugs, all of which have been unsuccessful to date in providing reliable efficacious treatment options for FIPV. Recently, antiviral studies investigating the broad-spectrum coronavirus protease inhibitor, GC376, and the adenosine nucleoside analogue GS-441524, have resulted in increased survival rates and clinical cure in many patients. However, prescriber access to these antiviral therapies is currently problematic as they have not yet obtained registration for veterinary use. Consequently, FIP remains challenging to treat. The purpose of this review is to provide an update on the current status of therapeutics for FIP. Additionally, due to interest in coronaviruses resulting from the current human pandemic, this review provides information on domesticated cats identified as SARS-CoV-2 positive. Twit Text FOAVip Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive cats ????Vet Q http://www.kidney.de/pget.php?&tw=1&pmid=33138721 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33138721 #FOAvip English Wikipedia <ref>{{Cite pmid|33138721}}</ref> Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive cats #MMPMID33138721 Izes AM; Yu J; Norris JM; Govendir M Vet Q 2020[Dec]; 40 (1): 322-330 PMID33138721show ga Feline infectious peritonitis (FIP) is a viral-induced, immune-mediated disease of cats caused by virulent biotypes of feline coronaviruses (FCoV), known as the feline infectious peritonitis virus (FIPV). Historically, three major pharmacological approaches have been employed to treat FIP: (1) immunomodulators to stimulate the patient's immune system non-specifically to reduce the clinical effects of the virus through a robust immune response, (2) immunosuppressive agents to dampen clinical signs temporarily, and (3) re-purposed human antiviral drugs, all of which have been unsuccessful to date in providing reliable efficacious treatment options for FIPV. Recently, antiviral studies investigating the broad-spectrum coronavirus protease inhibitor, GC376, and the adenosine nucleoside analogue GS-441524, have resulted in increased survival rates and clinical cure in many patients. However, prescriber access to these antiviral therapies is currently problematic as they have not yet obtained registration for veterinary use. Consequently, FIP remains challenging to treat. The purpose of this review is to provide an update on the current status of therapeutics for FIP. Additionally, due to interest in coronaviruses resulting from the current human pandemic, this review provides information on domesticated cats identified as SARS-CoV-2 positive. |*Betacoronavirus[MESH] |Animals[MESH] |Antiviral Agents/*therapeutic use[MESH] |COVID-19[MESH] |Cats[MESH] |Coronavirus Infections/drug therapy/*veterinary[MESH] |Feline Infectious Peritonitis/*drug therapy[MESH] |Immunologic Factors/*therapeutic use[MESH] |Pandemics/*veterinary[MESH] |Pneumonia, Viral/drug therapy/*veterinary[MESH]Current status on treatment options for feline infectious peritonitis (epmc).pdf DeepDyve Pubget Overpricing