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10.1016/j.diagmicrobio.2020.115248 http://scihub22266oqcxt.onion/10.1016/j.diagmicrobio.2020.115248 33130510!7562965!33130510     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diagn+Microbiol+Infect+Dis 2021 ; 99 (2): 115248 Nephropedia Template TP {{tp|p=33130510|t=2021. Evaluation of a SARS-CoV-2 lateral flow assay using the plaque reduction neutralization test |pdf=|usr=}}{{33130510}} gab.com Text Evaluation of a SARS-CoV-2 lateral flow assay using the plaque reduction neutralization test JO: Diagn Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33130510 #FOAvip As new tests and technologies advance our understanding and diagnostic capabilities of the severe acute respiratory syndrome coronavirus 2 and the coronavirus disease 2019, they must be appropriately validated to make sure test performance is following manufacturer claims. In this study, we evaluated the Vazyme 2019-nCoV IgG/IgM Detection Kit, which is a lateral flow assay (LFA), by the plaque reduction neutralization test (PRNT) using 100 patient plasma/serum samples. As compared to the PRNT results, the Vazyme LFA had 95.9% sensitivity and 96.1% specificity. Along with the increased need for rapid, effective, and affordable point of care tests to help provide meaningful epidemiological data, we demonstrated that the Vazyme LFA performed well on IgG detection but cannot be judged on the performance of IgM detection using PRNT alone. However, our observation of the low IgM-positive rate supported the poor performance of IgM detection of this LFA which led to the disapproval of its Emergency Use Authorization recently. Twit Text FOAVip Evaluation of a SARS-CoV-2 lateral flow assay using the plaque reduction neutralization test ????Diagn Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33130510 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33130510 #FOAvip English Wikipedia <ref>{{Cite pmid|33130510}}</ref> Evaluation of a SARS-CoV-2 lateral flow assay using the plaque reduction neutralization test #MMPMID33130510 Xie X; Nielsen MC; Muruato AE; Fontes-Garfias CR; Ren P Diagn Microbiol Infect Dis 2021[Feb]; 99 (2): 115248 PMID33130510show ga As new tests and technologies advance our understanding and diagnostic capabilities of the severe acute respiratory syndrome coronavirus 2 and the coronavirus disease 2019, they must be appropriately validated to make sure test performance is following manufacturer claims. In this study, we evaluated the Vazyme 2019-nCoV IgG/IgM Detection Kit, which is a lateral flow assay (LFA), by the plaque reduction neutralization test (PRNT) using 100 patient plasma/serum samples. As compared to the PRNT results, the Vazyme LFA had 95.9% sensitivity and 96.1% specificity. Along with the increased need for rapid, effective, and affordable point of care tests to help provide meaningful epidemiological data, we demonstrated that the Vazyme LFA performed well on IgG detection but cannot be judged on the performance of IgM detection using PRNT alone. However, our observation of the low IgM-positive rate supported the poor performance of IgM detection of this LFA which led to the disapproval of its Emergency Use Authorization recently. |Antibodies, Viral/*blood[MESH] |COVID-19/*diagnosis[MESH] |Humans[MESH] |Immunoassay/methods[MESH] |Immunoglobulin G/blood[MESH] |Immunoglobulin M/blood[MESH] |Neutralization Tests/*methods[MESH] |Point-of-Care Testing[MESH] |SARS-CoV-2/*immunology[MESH]Evaluation of a SARS-CoV-2 lateral flow assay using the plaque reducti(epmc).pdf DeepDyve Pubget Overpricing