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10.1016/j.lfs.2020.118676 http://scihub22266oqcxt.onion/10.1016/j.lfs.2020.118676 33129880!7598563!33129880     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Life+Sci 2021 ; 264 (ä): 118676 Nephropedia Template TP {{tp|p=33129880|t=2021. Is highly expressed ACE 2 in pregnant women "a curse" in times of COVID-19 pandemic?|pdf=|usr=}}{{33129880}} gab.com Text Is highly expressed ACE 2 in pregnant women "a curse" in times of COVID-19 pandemic JO: Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=33129880 #FOAvip Angiotensin-converting enzyme 2 (ACE 2) is a membrane-bound enzyme that cleaves angiotensin II (Ang II) into angiotensin (1-7). It also serves as an important binding site for SARS-CoV-2, thereby, facilitating viral entry into target host cells. ACE 2 is abundantly present in the intestine, kidney, heart, lungs, and fetal tissues. Fetal ACE 2 is involved in myocardium growth, lungs and brain development. ACE 2 is highly expressed in pregnant women to compensate preeclampsia by modulating angiotensin (1-7) which binds to the Mas receptor, having vasodilator action and maintain fluid homeostasis. There are reports available on Zika, H1N1 and SARS-CoV where these viruses have shown to produce fetal defects but very little is known about SARS-CoV-2 involvement in pregnancy, but it might have the potential to interact with fetal ACE 2 and enhance COVID-19 transmission to the fetus, leading to fetal morbidity and mortality. This review sheds light on a path of SARS-CoV-2 transmission risk in pregnancy and its possible link with fetal ACE 2. Twit Text FOAVip Is highly expressed ACE 2 in pregnant women "a curse" in times of COVID-19 pandemic ????Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=33129880 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33129880 #FOAvip English Wikipedia <ref>{{Cite pmid|33129880}}</ref> Is highly expressed ACE 2 in pregnant women "a curse" in times of COVID-19 pandemic? #MMPMID33129880 Dhaundiyal A; Kumari P; Jawalekar SS; Chauhan G; Kalra S; Navik U Life Sci 2021[Jan]; 264 (ä): 118676 PMID33129880show ga Angiotensin-converting enzyme 2 (ACE 2) is a membrane-bound enzyme that cleaves angiotensin II (Ang II) into angiotensin (1-7). It also serves as an important binding site for SARS-CoV-2, thereby, facilitating viral entry into target host cells. ACE 2 is abundantly present in the intestine, kidney, heart, lungs, and fetal tissues. Fetal ACE 2 is involved in myocardium growth, lungs and brain development. ACE 2 is highly expressed in pregnant women to compensate preeclampsia by modulating angiotensin (1-7) which binds to the Mas receptor, having vasodilator action and maintain fluid homeostasis. There are reports available on Zika, H1N1 and SARS-CoV where these viruses have shown to produce fetal defects but very little is known about SARS-CoV-2 involvement in pregnancy, but it might have the potential to interact with fetal ACE 2 and enhance COVID-19 transmission to the fetus, leading to fetal morbidity and mortality. This review sheds light on a path of SARS-CoV-2 transmission risk in pregnancy and its possible link with fetal ACE 2. |*Pandemics[MESH] |Adult[MESH] |Angiotensin-Converting Enzyme 2/chemistry/*genetics/metabolism[MESH] |COVID-19/diagnosis/*epidemiology/mortality/virology[MESH] |Female[MESH] |Fetal Mortality/trends[MESH] |Fetus[MESH] |Gene Expression Regulation[MESH] |Host-Pathogen Interactions/genetics[MESH] |Humans[MESH] |Kidney/virology[MESH] |Models, Molecular[MESH] |Placenta/*virology[MESH] |Pregnancy[MESH] |Protein Structure, Secondary[MESH] |Receptors, Virus/chemistry/*genetics/metabolism[MESH] |Renin-Angiotensin System/genetics[MESH] |SARS-CoV-2/pathogenicity[MESH] |Spike Glycoprotein, Coronavirus/chemistry/*genetics/metabolism[MESH]Is highly expressed ACE 2 in pregnant women "a curse" in times of COVI(epmc).pdf DeepDyve Pubget Overpricing