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10.3389/fimmu.2020.571897 http://scihub22266oqcxt.onion/10.3389/fimmu.2020.571897 33123148!7573146!33123148     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2020 ; 11 (ä): 571897 Nephropedia Template TP {{tp|p=33123148|t=2020. Potential for Targeting Myeloid Cells in Controlling CNS Inflammation |pdf=|usr=}}{{33123148}} gab.com Text Potential for Targeting Myeloid Cells in Controlling CNS Inflammation JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33123148 #FOAvip Multiple Sclerosis (MS) is characterized by immune cell infiltration to the central nervous system (CNS) as well as loss of myelin. Characterization of the cells in lesions of MS patients revealed an important accumulation of myeloid cells such as macrophages and dendritic cells (DCs). Data from the experimental autoimmune encephalomyelitis (EAE) model of MS supports the importance of peripheral myeloid cells in the disease pathology. However, the majority of MS therapies focus on lymphocytes. As we will discuss in this review, multiple strategies are now in place to target myeloid cells in clinical trials. These strategies have emerged from data in both human and mouse studies. We discuss strategies targeting myeloid cell migration, growth factors and cytokines, biological functions (with a focus on miRNAs), and immunological activities (with a focus on nanoparticles). Twit Text FOAVip Potential for Targeting Myeloid Cells in Controlling CNS Inflammation ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33123148 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33123148 #FOAvip English Wikipedia <ref>{{Cite pmid|33123148}}</ref> Potential for Targeting Myeloid Cells in Controlling CNS Inflammation #MMPMID33123148 Ifergan I; Miller SD Front Immunol 2020[]; 11 (ä): 571897 PMID33123148show ga Multiple Sclerosis (MS) is characterized by immune cell infiltration to the central nervous system (CNS) as well as loss of myelin. Characterization of the cells in lesions of MS patients revealed an important accumulation of myeloid cells such as macrophages and dendritic cells (DCs). Data from the experimental autoimmune encephalomyelitis (EAE) model of MS supports the importance of peripheral myeloid cells in the disease pathology. However, the majority of MS therapies focus on lymphocytes. As we will discuss in this review, multiple strategies are now in place to target myeloid cells in clinical trials. These strategies have emerged from data in both human and mouse studies. We discuss strategies targeting myeloid cell migration, growth factors and cytokines, biological functions (with a focus on miRNAs), and immunological activities (with a focus on nanoparticles). |Animals[MESH] |Cell Movement[MESH] |Central Nervous System/*physiology[MESH] |Cytokines/metabolism[MESH] |Encephalomyelitis, Autoimmune, Experimental/*therapy[MESH] |Humans[MESH] |Mice[MESH] |MicroRNAs/genetics[MESH] |Multiple Sclerosis/*therapy[MESH] |Myeloid Cells/*physiology[MESH] |Nanoparticles[MESH]Potential for Targeting Myeloid Cells in Controlling CNS Inflammation (epmc).pdf DeepDyve Pubget Overpricing