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10.1042/BST20200395 http://scihub22266oqcxt.onion/10.1042/BST20200395 33119046!7880721!33119046     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochem+Soc+Trans 2020 ; 48 (5): 2173-2184 Nephropedia Template TP {{tp|p=33119046|t=2020. ER functions are exploited by viruses to support distinct stages of their life cycle |pdf=|usr=}}{{33119046}} gab.com Text ER functions are exploited by viruses to support distinct stages of their life cycle JO: Biochem Soc Trans http://www.kidney.de/pget.php?&tw=1&pmid=33119046 #FOAvip The endoplasmic reticulum (ER), with its expansive membranous system and a vast network of chaperones, enzymes, sensors, and ion channels, orchestrates diverse cellular functions, ranging from protein synthesis, folding, secretion, and degradation to lipid biogenesis and calcium homeostasis. Strikingly, some of the functions of the ER are exploited by viruses to promote their life cycles. During entry, viruses must penetrate a host membrane and reach an intracellular destination to express and replicate their genomes. These events lead to the assembly of new viral progenies that exit the host cell, thereby initiating further rounds of infection. In this review, we highlight how three distinct viruses - polyomavirus, flavivirus, and coronavirus - co-opt key functions of the ER to cause infection. We anticipate that illuminating this virus-ER interplay will provide rational therapeutic approaches to combat the virus-induced diseases. Twit Text FOAVip ER functions are exploited by viruses to support distinct stages of their life cycle ????Biochem Soc Trans http://www.kidney.de/pget.php?&tw=1&pmid=33119046 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33119046 #FOAvip English Wikipedia <ref>{{Cite pmid|33119046}}</ref> ER functions are exploited by viruses to support distinct stages of their life cycle #MMPMID33119046 Chen YJ; Bagchi P; Tsai B Biochem Soc Trans 2020[Oct]; 48 (5): 2173-2184 PMID33119046show ga The endoplasmic reticulum (ER), with its expansive membranous system and a vast network of chaperones, enzymes, sensors, and ion channels, orchestrates diverse cellular functions, ranging from protein synthesis, folding, secretion, and degradation to lipid biogenesis and calcium homeostasis. Strikingly, some of the functions of the ER are exploited by viruses to promote their life cycles. During entry, viruses must penetrate a host membrane and reach an intracellular destination to express and replicate their genomes. These events lead to the assembly of new viral progenies that exit the host cell, thereby initiating further rounds of infection. In this review, we highlight how three distinct viruses - polyomavirus, flavivirus, and coronavirus - co-opt key functions of the ER to cause infection. We anticipate that illuminating this virus-ER interplay will provide rational therapeutic approaches to combat the virus-induced diseases. |*Host-Pathogen Interactions[MESH] |Coronavirus/*physiology[MESH] |Endoplasmic Reticulum/*metabolism[MESH] |Flavivirus/*physiology[MESH] |Humans[MESH] |Molecular Chaperones/metabolism[MESH] |Polyomavirus/*physiology[MESH] |Virus Diseases/metabolism/prevention & control[MESH] |Virus Internalization[MESH]ER functions are exploited by viruses to support distinct stages of th(epmc).pdf DeepDyve Pubget Overpricing