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10.1016/j.ijid.2020.10.043

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.10.043
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33115680!7585717!33115680
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suck abstract from ncbi


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pmid33115680      Int+J+Infect+Dis 2021 ; 102 (ä): 152-154
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  • Serological cross-reaction and coinfection of dengue and COVID-19 in Asia: Experience from Indonesia #MMPMID33115680
  • Masyeni S; Santoso MS; Widyaningsih PD; Asmara DW; Nainu F; Harapan H; Sasmono RT
  • Int J Infect Dis 2021[Jan]; 102 (ä): 152-154 PMID33115680show ga
  • Similar symptoms and laboratory findings between dengue and coronavirus disease 2019 (COVID-19) pose a diagnostic challenge in some dengue-endemic countries in Asia. In this study, we reported three cases of suspected COVID-19-dengue coinfection in hospitals of Bali, Indonesia. Serological data demonstrated that patients with positive results for dengue virus (DENV) NS1 antigen and anti-dengue IgM were also reactive to COVID-19 rapid antibody tests, suggesting dengue-COVID-19 coinfection. However, two patients were later confirmed negative for SARS-COV-2 by qRT-PCR, implying a plausible cross-reactivity of anti-dengue and anti-COVID-19 antibodies in the serological test. Coinfection of dengue and COVID-19 was evident in one patient, following confirmation of SARS-COV-2 by qRT-PCR and DENV infection using the NS1 antigen serology test. This case was the first case of dengue and COVID-19 coinfection in Indonesia and revealed possible cross-reactivity between SARS-COV-2 and DENV antibodies based on rapid serological tests. Our study indicates a public health concern regarding COVID-19 and dengue detection in Indonesia as well as in other dengue-endemic countries, and it is important for these nations to manage both pathogens concurrently.
  • |*COVID-19 Serological Testing[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19/*diagnosis/immunology[MESH]
  • |Coinfection/*diagnosis/immunology[MESH]
  • |Cross Reactions[MESH]
  • |Dengue Virus/*immunology[MESH]
  • |Dengue/*diagnosis[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]


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