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10.1016/j.biochi.2020.10.010 http://scihub22266oqcxt.onion/10.1016/j.biochi.2020.10.010 33115667!7585727!33115667     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochimie 2020 ; 179 (ä): 229-236 Nephropedia Template TP {{tp|p=33115667|t=2020. Membrane heist: Coronavirus host membrane remodeling during replication |pdf=|usr=}}{{33115667}} gab.com Text Membrane heist: Coronavirus host membrane remodeling during replication JO: Biochimie http://www.kidney.de/pget.php?&tw=1&pmid=33115667 #FOAvip The ongoing pandemic of COVID-19 (Coronavirus Disease-2019), a respiratory disease caused by the novel coronavirus strain, SARS-CoV-2, has affected more than 42 million people already, with more than one million deaths worldwide (as of October 25, 2020). We are in urgent need of therapeutic interventions that target the host-virus interface, which requires a molecular understanding of the SARS-CoV-2 life-cycle. Like other positive-sense RNA viruses, coronaviruses remodel intracellular membranes to form specialized viral replication compartments, including double-membrane vesicles (DMVs), where viral RNA genome replication takes place. Here we review the current knowledge of the structure, lipid composition, function, and biogenesis of coronavirus-induced DMVs, highlighting the druggable viral and cellular factors that are involved in the formation and function of DMVs. Twit Text FOAVip Membrane heist: Coronavirus host membrane remodeling during replication ????Biochimie http://www.kidney.de/pget.php?&tw=1&pmid=33115667 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33115667 #FOAvip English Wikipedia <ref>{{Cite pmid|33115667}}</ref> Membrane heist: Coronavirus host membrane remodeling during replication #MMPMID33115667 Zhang J; Lan Y; Sanyal S Biochimie 2020[Dec]; 179 (ä): 229-236 PMID33115667show ga The ongoing pandemic of COVID-19 (Coronavirus Disease-2019), a respiratory disease caused by the novel coronavirus strain, SARS-CoV-2, has affected more than 42 million people already, with more than one million deaths worldwide (as of October 25, 2020). We are in urgent need of therapeutic interventions that target the host-virus interface, which requires a molecular understanding of the SARS-CoV-2 life-cycle. Like other positive-sense RNA viruses, coronaviruses remodel intracellular membranes to form specialized viral replication compartments, including double-membrane vesicles (DMVs), where viral RNA genome replication takes place. Here we review the current knowledge of the structure, lipid composition, function, and biogenesis of coronavirus-induced DMVs, highlighting the druggable viral and cellular factors that are involved in the formation and function of DMVs. |*Host Microbial Interactions[MESH] |*Virus Replication[MESH] |Cell Membrane/*metabolism/virology[MESH] |Coronavirus/*physiology[MESH] |Humans[MESH]Membrane heist: Coronavirus host membrane remodeling during replicatio(epmc).pdf DeepDyve Pubget Overpricing