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10.1371/journal.pone.0241100

http://scihub22266oqcxt.onion/10.1371/journal.pone.0241100
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33108384!7591034!33108384
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suck abstract from ncbi


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pmid33108384      PLoS+One 2020 ; 15 (10): e0241100
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  • A comparison of health care worker-collected foam and polyester nasal swabs in convalescent COVID-19 patients #MMPMID33108384
  • Hart B; Tu YP; Jennings R; Verma P; Padgett LR; Rains D; Vojta D; Berke EM
  • PLoS One 2020[]; 15 (10): e0241100 PMID33108384show ga
  • Both polyester and foam nasal swabs were collected from convalescent COVID-19 patients at a single visit and stored in viral transport media (VTM), saline or dry. Sensitivity of each swab material and media combination were estimated, three by three tables were constructed to measure polyester and foam concordance, and cycle threshold (Ct) values were compared. 126 visits had polyester and foam swabs stored in viral transport media (VTM), 51 had swabs stored in saline, and 63 had a foam swab in VTM and a polyester swab stored in a dry tube. Polyester and foam swabs had an estimated sensitivity of 87.3% and 94.5% respectively in VTM, 87.5% and 93.8% respectively in saline, and 75.0% and 90.6% respectively for dry polyester and foam VTM. Polyester and foam Ct values were correlated, but polyester showed decreased performance for cases with a viral load near the detection threshold and higher Ct values on average.
  • |*Clinical Laboratory Techniques[MESH]
  • |*Convalescence[MESH]
  • |*Pandemics[MESH]
  • |*Polyesters[MESH]
  • |*Polyurethanes[MESH]
  • |Adult[MESH]
  • |Betacoronavirus/genetics/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Coronavirus Infections/diagnosis/*virology[MESH]
  • |Culture Media[MESH]
  • |Disposable Equipment/supply & distribution[MESH]
  • |Female[MESH]
  • |Health Personnel[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasal Cavity/*virology[MESH]
  • |Pneumonia, Viral/diagnosis/*virology[MESH]
  • |RNA, Viral/analysis[MESH]
  • |Random Allocation[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Saline Solution[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Specimen Handling/*instrumentation/methods[MESH]


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