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10.1080/14760584.2020.1843432

http://scihub22266oqcxt.onion/10.1080/14760584.2020.1843432
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33107353!ä!33107353

suck abstract from ncbi


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pmid33107353      Expert+Rev+Vaccines 2020 ; 19 (10): 937-947
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  • COVID-19 in health-care workers: lessons from SARS and MERS epidemics and perspectives for chemoprophylaxis and vaccines #MMPMID33107353
  • Labetoulle R; Detoc M; Gagnaire J; Berthelot P; Pelissier C; Fontana L; Botelho-Nevers E; Gagneux-Brunon A
  • Expert Rev Vaccines 2020[Oct]; 19 (10): 937-947 PMID33107353show ga
  • Introduction: The world is now facing the COVID-19 pandemic. Experience with SARS-CoV and MERS-CoV, and early reports about SARS-CoV-2 infection suggest that health-care settings and health-care workers (HCWs) are vulnerable in the context of the emergence of a new coronavirus. Areas covered: To highlight the need for prophylactic strategies particularly for HCWs, we identified SARS-CoV, MERS-CoV, and SARS-CoV-2 outbreaks in health-care settings and the incidence of infections in HCWs by a search on MEDLINE and MEDxRIV (for SARS-Cov-2). To identify prophylactic strategies against, we conducted a search on MEDLINE and clinicaltrials.gov about studies involving SARS-CoV, MERS-CoV, and SARS-CoV-2. Expert opinion: HCWs account for a great part of SARS, MERS, and SARS-CoV-2 infections, they may also contribute to the spread of the disease, particularly in health-care settings, and contribute to nosocomial outbreaks. Some preventive strategies were evaluated in previous emerging coronavirus epidemics, particularly in MERS-CoV. For COVID-19 prevention, different chemoprophylaxis with drug repositioning and new agents are under evaluation, and different vaccine candidates entered clinical development, with clinical trials. HCWs are a crucial target population for pre-exposure and post-exposure prophylaxis.
  • |*Health Personnel[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19 Vaccines/administration & dosage[MESH]
  • |COVID-19/epidemiology/*prevention & control[MESH]
  • |Coronavirus Infections/epidemiology[MESH]
  • |Drug Development[MESH]
  • |Drug Repositioning[MESH]
  • |Humans[MESH]
  • |Infectious Disease Transmission, Patient-to-Professional/*prevention & control[MESH]
  • |Post-Exposure Prophylaxis[MESH]


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