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10.1007/s10930-020-09935-8 http://scihub22266oqcxt.onion/10.1007/s10930-020-09935-8 33106987!7587547!33106987     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Protein+J 2020 ; 39 (6): 644-656 Nephropedia Template TP {{tp|p=33106987|t=2020. Role of Oxidative Stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) Infection: A Review |pdf=|usr=}}{{33106987}} gab.com Text Role of Oxidative Stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) Infection: A Review JO: Protein J http://www.kidney.de/pget.php?&tw=1&pmid=33106987 #FOAvip Novel coronavirus disease 2019 (COVID-19) has resulted in a global pandemic and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several studies have suggested that a precise disulfide-thiol balance is crucial for viral entry and fusion into the host cell and that oxidative stress generated from free radicals can affect this balance. Here, we reviewed the current knowledge about the role of oxidative stress on SARS-CoV and SARS-CoV-2 infections. We focused on the impact of antioxidants, like NADPH and glutathione, and redox proteins, such as thioredoxin and protein disulfide isomerase, that maintain the disulfide-thiol balance in the cell. The possible influence of these biomolecules on the binding of viral protein with the host cell angiotensin-converting enzyme II receptor protein as well as on the severity of COVID-19 infection was discussed. Twit Text FOAVip Role of Oxidative Stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) Infection: A Review ????Protein J http://www.kidney.de/pget.php?&tw=1&pmid=33106987 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33106987 #FOAvip English Wikipedia <ref>{{Cite pmid|33106987}}</ref> Role of Oxidative Stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) Infection: A Review #MMPMID33106987 Suhail S; Zajac J; Fossum C; Lowater H; McCracken C; Severson N; Laatsch B; Narkiewicz-Jodko A; Johnson B; Liebau J; Bhattacharyya S; Hati S Protein J 2020[Dec]; 39 (6): 644-656 PMID33106987show ga Novel coronavirus disease 2019 (COVID-19) has resulted in a global pandemic and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several studies have suggested that a precise disulfide-thiol balance is crucial for viral entry and fusion into the host cell and that oxidative stress generated from free radicals can affect this balance. Here, we reviewed the current knowledge about the role of oxidative stress on SARS-CoV and SARS-CoV-2 infections. We focused on the impact of antioxidants, like NADPH and glutathione, and redox proteins, such as thioredoxin and protein disulfide isomerase, that maintain the disulfide-thiol balance in the cell. The possible influence of these biomolecules on the binding of viral protein with the host cell angiotensin-converting enzyme II receptor protein as well as on the severity of COVID-19 infection was discussed. |*Oxidative Stress/drug effects[MESH] |Acetylcysteine/pharmacology[MESH] |Angiotensin-Converting Enzyme 2/metabolism[MESH] |Animals[MESH] |Antiviral Agents/pharmacology[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/*metabolism[MESH] |Drug Discovery[MESH] |Humans[MESH] |Models, Molecular[MESH] |SARS-CoV-2/drug effects/*physiology[MESH] |Severe Acute Respiratory Syndrome/drug therapy/*metabolism[MESH] |Severe acute respiratory syndrome-related coronavirus/*physiology[MESH] |Spike Glycoprotein, Coronavirus/metabolism[MESH]Role of Oxidative Stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) (epmc).pdf DeepDyve Pubget Overpricing