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10.1007/s42399-020-00602-8

http://scihub22266oqcxt.onion/10.1007/s42399-020-00602-8
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suck abstract from ncbi


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pmid33106783      SN+Compr+Clin+Med 2020 ; 2 (11): 2077-2085
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  • Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2: a New Challenge amid the Pandemic #MMPMID33106783
  • Lawrensia S; Henrina J; Wijaya E; Suciadi LP; Saboe A; Cool CJ
  • SN Compr Clin Med 2020[]; 2 (11): 2077-2085 PMID33106783show ga
  • Initially, SARS-CoV-2 infection had been reported as a relatively mild case in children than in adults. Nevertheless, recent evidence found that a subset of children then developed a significant systemic inflammatory response that resembles atypical/typical Kawasaki's disease (KD) and toxic shock syndrome. This novel clinical syndrome later identified as pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). In contrast with KD, PIMS-TS appears to occur in children at an older age with a predominance of gastrointestinal symptoms, hemodynamic instability, and myocardial dysfunction. However, the exact pathomechanism remains to be understood. Nevertheless, the post-viral immunological reaction is postulated to be the underlying mechanistic underpinnings. The multifaceted nature of the PIMS-TS' course underlines the need for early recognition and multispecialty care and management.
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