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10.1136/openhrt-2020-001432 http://scihub22266oqcxt.onion/10.1136/openhrt-2020-001432 33106441!7592245!33106441     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Open+Heart 2020 ; 7 (2): ä Nephropedia Template TP {{tp|p=33106441|t=2020. COVID-19 pandemic and STEMI: pathway activation and outcomes from the pan-London heart attack group |pdf=|usr=}}{{33106441}} gab.com Text COVID-19 pandemic and STEMI: pathway activation and outcomes from the pan-London heart attack group JO: Open Heart http://www.kidney.de/pget.php?&tw=1&pmid=33106441 #FOAvip OBJECTIVES: To understand the impact of COVID-19 on delivery and outcomes of primary percutaneous coronary intervention (PPCI). Furthermore, to compare clinical presentation and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) with active COVID-19 against those without COVID-19. METHODS: We systematically analysed 348 STEMI cases presenting to the PPCI programme in London during the peak of the pandemic (1 March to 30 April 2020) and compared with 440 cases from the same period in 2019. Outcomes of interest included ambulance response times, timeliness of revascularisation, angiographic and procedural characteristics, and in-hospital clinical outcomes RESULTS: There was a 21% reduction in STEMI admissions and longer ambulance response times (87 (62-118) min in 2020 vs 75 (57-95) min in 2019, p<0.001), but that this was not associated with a delays in achieving revascularisation once in hospital (48 (34-65) min in 2020 vs 48 (35-70) min in 2019, p=0.35) or increased mortality (10.9% (38) in 2020 vs 8.6% (38) in 2019, p=0.28). 46 patients with active COVID-19 were more thrombotic and more likely to have intensive care unit admissions (32.6% (15) vs 9.3% (28), OR 5.74 (95%CI 2.24 to 9.89), p<0.001). They also had increased length of stay (4 (3-9) days vs 3 (2-4) days, p<0.001) and a higher mortality (21.7% (10) vs 9.3% (28), OR 2.72 (95% CI 1.25 to 5.82), p=0.012) compared with patients having PPCI without COVID-19. CONCLUSION: These findings suggest that PPCI pathways can be maintained during unprecedented healthcare emergencies but confirms the high mortality of STEMI in the context of concomitant COVID-19 infection characterised by a heightened state of thrombogenicity. Twit Text FOAVip COVID-19 pandemic and STEMI: pathway activation and outcomes from the pan-London heart attack group ????Open Heart http://www.kidney.de/pget.php?&tw=1&pmid=33106441 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33106441 #FOAvip English Wikipedia <ref>{{Cite pmid|33106441}}</ref> COVID-19 pandemic and STEMI: pathway activation and outcomes from the pan-London heart attack group #MMPMID33106441 Little CD; Kotecha T; Candilio L; Jabbour RJ; Collins GB; Ahmed A; Connolly M; Kanyal R; Demir OM; Lawson LO; Wang B; Firoozi S; Spratt JC; Perera D; MacCarthy P; Dalby M; Jain A; Wilson SJ; Malik I; Rakhit R Open Heart 2020[Oct]; 7 (2): ä PMID33106441show ga OBJECTIVES: To understand the impact of COVID-19 on delivery and outcomes of primary percutaneous coronary intervention (PPCI). Furthermore, to compare clinical presentation and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) with active COVID-19 against those without COVID-19. METHODS: We systematically analysed 348 STEMI cases presenting to the PPCI programme in London during the peak of the pandemic (1 March to 30 April 2020) and compared with 440 cases from the same period in 2019. Outcomes of interest included ambulance response times, timeliness of revascularisation, angiographic and procedural characteristics, and in-hospital clinical outcomes RESULTS: There was a 21% reduction in STEMI admissions and longer ambulance response times (87 (62-118) min in 2020 vs 75 (57-95) min in 2019, p<0.001), but that this was not associated with a delays in achieving revascularisation once in hospital (48 (34-65) min in 2020 vs 48 (35-70) min in 2019, p=0.35) or increased mortality (10.9% (38) in 2020 vs 8.6% (38) in 2019, p=0.28). 46 patients with active COVID-19 were more thrombotic and more likely to have intensive care unit admissions (32.6% (15) vs 9.3% (28), OR 5.74 (95%CI 2.24 to 9.89), p<0.001). They also had increased length of stay (4 (3-9) days vs 3 (2-4) days, p<0.001) and a higher mortality (21.7% (10) vs 9.3% (28), OR 2.72 (95% CI 1.25 to 5.82), p=0.012) compared with patients having PPCI without COVID-19. CONCLUSION: These findings suggest that PPCI pathways can be maintained during unprecedented healthcare emergencies but confirms the high mortality of STEMI in the context of concomitant COVID-19 infection characterised by a heightened state of thrombogenicity. |*Coronavirus Infections/diagnosis/mortality/therapy/transmission[MESH] |*Pandemics[MESH] |*Percutaneous Coronary Intervention/adverse effects/mortality[MESH] |*Pneumonia, Viral/diagnosis/mortality/therapy/transmission[MESH] |Aged[MESH] |Ambulances/organization & administration[MESH] |COVID-19[MESH] |Critical Pathways/*organization & administration[MESH] |Databases, Factual[MESH] |Delivery of Health Care, Integrated/*organization & administration[MESH] |Female[MESH] |Hospital Mortality[MESH] |Humans[MESH] |Length of Stay[MESH] |London/epidemiology[MESH] |Male[MESH] |Middle Aged[MESH] |Outcome and Process Assessment, Health Care/*organization & administration[MESH] |Patient Admission[MESH] |Patient Safety[MESH] |Retrospective Studies[MESH] |Risk Assessment[MESH] |Risk Factors[MESH] |ST Elevation Myocardial Infarction/diagnosis/mortality/*therapy[MESH] |Thrombosis/mortality/therapy[MESH] |Time Factors[MESH] |Time-to-Treatment/organization & administration[MESH]COVID-19 pandemic and STEMI: pathway activation and outcomes from the (epmc).pdf DeepDyve Pubget Overpricing