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10.1111/ijlh.13374 http://scihub22266oqcxt.onion/10.1111/ijlh.13374 33099889!ä!33099889 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Lab+Hematol 2021 ; 43 (2): 329-335 Nephropedia Template TP {{tp|p=33099889|t=2021. Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19 |pdf=|usr=}}{{33099889}} gab.com Text Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19 JO: Int J Lab Hematol http://www.kidney.de/pget.php?&tw=1&pmid=33099889 #FOAvip INTRODUCTION: Monitoring of laboratory indicators is important for predicting changes in disease severity and clinical outcomes. We aimed to identify the critical predictors that can effectively assess the disease conditions of patients with COVID-19 by analyzing the clinical characteristics and laboratory findings of patients with SARS-CoV-2 infection. METHODS: All consecutive patients (n = 294) with confirmed SARS-CoV-2 infection admitted to the General Hospital of Central Theater Command of the PLA from February 6 to February 21, 2020, were enrolled. These patients were divided into the severe group and the nonsevere group according to disease severity during hospitalization. RESULTS: The median neutrophil-to-lymphocyte ratio (NLR) value of the severe patients was dramatically higher than that of the nonsevere patients (10.4 vs 2.6; P < .001). The NLR value equal to 5 was a boundary value worthy of reference, because more than 80% severe patients had an NLR value greater than 5 and over 80% nonsevere patients had an NLR value less than 5. The NLR value of these COVID-19 patients was positively and respectively correlated with the values of C-reactive protein (R = .5921, P < .001), lactate dehydrogenase (R = .4509, P < .001), procalcitonin (R = .5504, P < .001), fibrinogen (R = .4710, P < .001), and D-dimers (R = .4425, P < .001). However, the NLR value was merely and positively correlated with the interleukin-6 value (R = .3594, P < .05), but had no correlations with the values of interleukin-10, interleukin-4, interleukin-17, interferon-gamma, and tumor necrosis factor-alpha (P > .05). DISCUSSION: Neutrophil-to-lymphocyte ratio is a critical predictor for assessment of disease severity in patients with COVID-19, and it has a close relation with the laboratory indicators related to disease conditions. Twit Text FOAVip Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19 ????Int J Lab Hematol http://www.kidney.de/pget.php?&tw=1&pmid=33099889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33099889 #FOAvip English Wikipedia <ref>{{Cite pmid|33099889}}</ref> Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19 #MMPMID33099889 Liu L; Zheng Y; Cai L; Wu W; Tang S; Ding Y; Liu W; Kou G; Xiong Z; Wang S; Zheng S Int J Lab Hematol 2021[Apr]; 43 (2): 329-335 PMID33099889show ga INTRODUCTION: Monitoring of laboratory indicators is important for predicting changes in disease severity and clinical outcomes. We aimed to identify the critical predictors that can effectively assess the disease conditions of patients with COVID-19 by analyzing the clinical characteristics and laboratory findings of patients with SARS-CoV-2 infection. METHODS: All consecutive patients (n = 294) with confirmed SARS-CoV-2 infection admitted to the General Hospital of Central Theater Command of the PLA from February 6 to February 21, 2020, were enrolled. These patients were divided into the severe group and the nonsevere group according to disease severity during hospitalization. RESULTS: The median neutrophil-to-lymphocyte ratio (NLR) value of the severe patients was dramatically higher than that of the nonsevere patients (10.4 vs 2.6; P < .001). The NLR value equal to 5 was a boundary value worthy of reference, because more than 80% severe patients had an NLR value greater than 5 and over 80% nonsevere patients had an NLR value less than 5. The NLR value of these COVID-19 patients was positively and respectively correlated with the values of C-reactive protein (R = .5921, P < .001), lactate dehydrogenase (R = .4509, P < .001), procalcitonin (R = .5504, P < .001), fibrinogen (R = .4710, P < .001), and D-dimers (R = .4425, P < .001). However, the NLR value was merely and positively correlated with the interleukin-6 value (R = .3594, P < .05), but had no correlations with the values of interleukin-10, interleukin-4, interleukin-17, interferon-gamma, and tumor necrosis factor-alpha (P > .05). DISCUSSION: Neutrophil-to-lymphocyte ratio is a critical predictor for assessment of disease severity in patients with COVID-19, and it has a close relation with the laboratory indicators related to disease conditions. |Adolescent[MESH] |Adult[MESH] |Age Factors[MESH] |Aged[MESH] |Biomarkers/blood[MESH] |C-Reactive Protein/*metabolism[MESH] |COVID-19/blood/*diagnosis/pathology/virology[MESH] |Female[MESH] |Fibrin Fibrinogen Degradation Products/*metabolism[MESH] |Fibrinogen/metabolism[MESH] |Humans[MESH] |Interleukin-6/blood[MESH] |L-Lactate Dehydrogenase/blood[MESH] |Male[MESH] |Middle Aged[MESH] |Neutrophils/immunology/*pathology/virology[MESH] |Predictive Value of Tests[MESH] |Procalcitonin/blood[MESH] |Retrospective Studies[MESH] |SARS-CoV-2/immunology/*pathogenicity[MESH] |Severity of Illness Index[MESH] |Sex Factors[MESH]Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of(epmc).pdf DeepDyve Pubget Overpricing