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10.1038/s41415-020-2228-9

http://scihub22266oqcxt.onion/10.1038/s41415-020-2228-9
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33097885!7582419!33097885
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suck abstract from ncbi


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pmid33097885      Br+Dent+J 2020 ; 229 (8): 521-524
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  • Non-infectious status indicated by detectable IgG antibody to SARS-CoV-2 #MMPMID33097885
  • Denning DW; Kilcoyne A; Ucer C
  • Br Dent J 2020[Oct]; 229 (8): 521-524 PMID33097885show ga
  • A key tenet of protection from infection for dentists is to know who is not infectious. The evidence base regarding protection from respiratory pathogens in dentistry is poor. Those with a positive SARS-CoV-2 IgG antibody are non-infectious (>99% certainty) and can be safely treated with good universal precautions, even for aerosol generating procedures. Viral infectivity with SARS-CoV-2 lasts eight days, unlike viral polymerase chain reaction (PCR) swab tests which can persist for as long as seven weeks. SARS-CoV-2 IgG antibody becomes detectable from 11 days after infection. SARS-CoV-2 IgG antibodies are usually neutralising against the virus and their direct antiviral activity was partially demonstrated in 33,000 patients with COVID-19 treated with convalescent plasma in the USA. So, a positive SARS-CoV-2 IgG antibody is a much more accurate determination of infectiousness than a repeat PCR which is only 70% sensitive. It remains to be seen whether SARS-Cov-2 vaccine responses include protective IgG titres and, once vaccines become widespread, can be used to assist decision-making on appropriate personal protective equipment (PPE) in dentistry.
  • |*Coronavirus Infections/prevention & control/therapy[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral[MESH]
  • |*Severe acute respiratory syndrome-related coronavirus[MESH]
  • |Antibodies, Viral[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Humans[MESH]
  • |Immunization, Passive[MESH]
  • |Immunoglobulin G[MESH]
  • |SARS-CoV-2[MESH]


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