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10.1088/1752-7163/abb762 http://scihub22266oqcxt.onion/10.1088/1752-7163/abb762 33089824!ä!33089824 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Breath+Res 2020 ; 15 (1): 011001 Nephropedia Template TP {{tp|p=33089824|t=2020. Rapid non-invasive detection of Influenza-A-infection by multicapillary column coupled ion mobility spectrometry |pdf=|usr=}}{{33089824}} gab.com Text Rapid non-invasive detection of Influenza-A-infection by multicapillary column coupled ion mobility spectrometry JO: J Breath Res http://www.kidney.de/pget.php?&tw=1&pmid=33089824 #FOAvip Infectious pathogens are a global issue. Global air travel offers an easy and fast opportunity not only for people but also for infectious diseases to spread around the world within a few days. Also, large public events facilitate increasing infection numbers. Therefore, rapid on-site screening for infected people is urgently needed. Due to the small size and easy handling, ion mobility spectrometry coupled with a multicapillary column (MCC-IMS) is a very promising, sensitive method for the on-site identification of infectious pathogens based on scents, representing volatile organic compounds (VOCs). The purpose of this study was to prospectively assess whether identification of Influenza-A-infection based on VOCs by MCC-IMS is possible in breath. Nasal breath was investigated in 24 consecutive persons with and without Influenza-A-infection by MCC-IMS. In 14 Influenza-A-infected patients, infection was proven by PCR of nasopharyngeal swabs. Four healthy staff members and six patients with negative PCR result served as controls. For picking up relevant VOCs in MCC-IMS spectra, software based on cluster analysis followed by multivariate statistical analysis was applied. With only four VOCs canonical discriminant analysis was able to distinguish Influenza-A-infected patients from those not infected with 100% sensitivity and 100% specificity. This present proof-of-concept-study yields encouraging results showing a rapid diagnosis of viral infections in nasal breath within 5 min by MCC-IMS. The next step is to validate the results with a greater number of patients with Influenza-A-infection as well as other viral diseases, especially COVID-19. Registration number at ClinicalTrials.gov NCT04282135. Twit Text FOAVip Rapid non-invasive detection of Influenza-A-infection by multicapillary column coupled ion mobility spectrometry ????J Breath Res http://www.kidney.de/pget.php?&tw=1&pmid=33089824 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33089824 #FOAvip English Wikipedia <ref>{{Cite pmid|33089824}}</ref> Rapid non-invasive detection of Influenza-A-infection by multicapillary column coupled ion mobility spectrometry #MMPMID33089824 Steppert C; Steppert I; Bollinger T; Sterlacci W J Breath Res 2020[Oct]; 15 (1): 011001 PMID33089824show ga Infectious pathogens are a global issue. Global air travel offers an easy and fast opportunity not only for people but also for infectious diseases to spread around the world within a few days. Also, large public events facilitate increasing infection numbers. Therefore, rapid on-site screening for infected people is urgently needed. Due to the small size and easy handling, ion mobility spectrometry coupled with a multicapillary column (MCC-IMS) is a very promising, sensitive method for the on-site identification of infectious pathogens based on scents, representing volatile organic compounds (VOCs). The purpose of this study was to prospectively assess whether identification of Influenza-A-infection based on VOCs by MCC-IMS is possible in breath. Nasal breath was investigated in 24 consecutive persons with and without Influenza-A-infection by MCC-IMS. In 14 Influenza-A-infected patients, infection was proven by PCR of nasopharyngeal swabs. Four healthy staff members and six patients with negative PCR result served as controls. For picking up relevant VOCs in MCC-IMS spectra, software based on cluster analysis followed by multivariate statistical analysis was applied. With only four VOCs canonical discriminant analysis was able to distinguish Influenza-A-infected patients from those not infected with 100% sensitivity and 100% specificity. This present proof-of-concept-study yields encouraging results showing a rapid diagnosis of viral infections in nasal breath within 5 min by MCC-IMS. The next step is to validate the results with a greater number of patients with Influenza-A-infection as well as other viral diseases, especially COVID-19. Registration number at ClinicalTrials.gov NCT04282135. |Aged[MESH] |Betacoronavirus/*isolation & purification[MESH] |Breath Tests[MESH] |COVID-19[MESH] |Coronavirus Infections/complications/*diagnosis[MESH] |Discriminant Analysis[MESH] |Female[MESH] |Humans[MESH] |Influenza A virus/*isolation & purification[MESH] |Influenza, Human/complications/*diagnosis[MESH] |Ion Mobility Spectrometry[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/complications/*diagnosis[MESH] |Prospective Studies[MESH] |SARS-CoV-2[MESH]Rapid non-invasive detection of Influenza-A-infection by multicapillar(epmc).pdf DeepDyve Pubget Overpricing