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10.1093/ehjcr/ytaa188

http://scihub22266oqcxt.onion/10.1093/ehjcr/ytaa188
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33089052!7454490!33089052
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suck abstract from ncbi

pmid33089052      Eur+Heart+J+Case+Rep 2020 ; 4 (FI1): 1-6
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  • Successful treatment of acute heart failure in COVID-19-induced cytokine storm with tocilizumab: a case report #MMPMID33089052
  • Chitturi KR; Thacker S; Al-Saadi MA; Kassi M
  • Eur Heart J Case Rep 2020[Oct]; 4 (FI1): 1-6 PMID33089052show ga
  • BACKGROUND: SARS-CoV-2 is known to induce a cytokine storm, a hyperinflammatory state driven by up-regulation of interleukin 6 (IL-6) and immunomodulatory chemokines that may result in acute heart failure. CASE SUMMARY: A 65-year-old woman with confirmed SARS-CoV-2 developed shock with multiorgan system failure, including acute biventricular heart failure, 2 weeks after the initial onset of fever, cough, and shortness of breath. The patient experienced myocardial recovery within 48 h after administration of tocilizumab, a humanized monoclonal anti-IL-6 receptor antibody, and multiple supportive vasoactive medications. DISCUSSION: The differential diagnosis of acute heart failure in critically ill patients with COVID-19 infection is broad, including sepsis-induced cardiomyopathy, Takotsubo syndrome, viral lymphocytic myocarditis, and acute coronary syndrome. Immunomodulatory treatment with tocilizumab may benefit patients who develop cardiogenic shock associated with SARS-CoV-2-induced cytokine storm.
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