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10.1186/s13148-020-00946-x http://scihub22266oqcxt.onion/10.1186/s13148-020-00946-x 33087172!7576975!33087172     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Epigenetics 2020 ; 12 (1): 156 Nephropedia Template TP {{tp|p=33087172|t=2020. The epigenetic implication in coronavirus infection and therapy |pdf=|usr=}}{{33087172}} gab.com Text The epigenetic implication in coronavirus infection and therapy JO: Clin Epigenetics http://www.kidney.de/pget.php?&tw=1&pmid=33087172 #FOAvip Epigenetics is a relatively new field of science that studies the genetic and non-genetic aspects related to heritable phenotypic changes, frequently caused by environmental and metabolic factors. In the host, the epigenetic machinery can regulate gene expression through a series of reversible epigenetic modifications, such as histone methylation and acetylation, DNA/RNA methylation, chromatin remodeling, and non-coding RNAs. The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection. The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China, and spread worldwide, causes it. COVID-19 severity and consequences largely depend on patient age and health status. In this review, we will summarize and comparatively analyze how viruses regulate the host epigenome. Mainly, we will be focusing on highly pathogenic respiratory RNA virus infections such as coronaviruses. In this context, epigenetic alterations might play an essential role in the onset of coronavirus disease complications. Although many therapeutic approaches are under study, more research is urgently needed to identify effective vaccine or safer chemotherapeutic drugs, including epigenetic drugs, to cope with this viral outbreak and to develop pre- and post-exposure prophylaxis against COVID-19. Twit Text FOAVip The epigenetic implication in coronavirus infection and therapy ????Clin Epigenetics http://www.kidney.de/pget.php?&tw=1&pmid=33087172 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33087172 #FOAvip English Wikipedia <ref>{{Cite pmid|33087172}}</ref> The epigenetic implication in coronavirus infection and therapy #MMPMID33087172 Atlante S; Mongelli A; Barbi V; Martelli F; Farsetti A; Gaetano C Clin Epigenetics 2020[Oct]; 12 (1): 156 PMID33087172show ga Epigenetics is a relatively new field of science that studies the genetic and non-genetic aspects related to heritable phenotypic changes, frequently caused by environmental and metabolic factors. In the host, the epigenetic machinery can regulate gene expression through a series of reversible epigenetic modifications, such as histone methylation and acetylation, DNA/RNA methylation, chromatin remodeling, and non-coding RNAs. The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection. The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China, and spread worldwide, causes it. COVID-19 severity and consequences largely depend on patient age and health status. In this review, we will summarize and comparatively analyze how viruses regulate the host epigenome. Mainly, we will be focusing on highly pathogenic respiratory RNA virus infections such as coronaviruses. In this context, epigenetic alterations might play an essential role in the onset of coronavirus disease complications. Although many therapeutic approaches are under study, more research is urgently needed to identify effective vaccine or safer chemotherapeutic drugs, including epigenetic drugs, to cope with this viral outbreak and to develop pre- and post-exposure prophylaxis against COVID-19. |*Epigenesis, Genetic[MESH] |*Gene Expression Regulation, Viral/drug effects[MESH] |Antiviral Agents/*pharmacology[MESH] |Betacoronavirus/*physiology[MESH] |COVID-19[MESH] |Coronavirus Infections/*drug therapy/*genetics/immunology[MESH] |Cytokines/genetics/immunology[MESH] |Host-Pathogen Interactions[MESH] |Humans[MESH] |Inflammation/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy/*genetics/immunology[MESH] |RNA Processing, Post-Transcriptional[MESH]The epigenetic implication in coronavirus infection and therapy (epmc).pdf DeepDyve Pubget Overpricing