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10.1093/ecco-jcc/jjaa135

http://scihub22266oqcxt.onion/10.1093/ecco-jcc/jjaa135
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suck abstract from ncbi


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pmid33085972      J+Crohns+Colitis 2020 ; 14 (14 Suppl 3): S769-S773
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  • Guidance for Restarting Inflammatory Bowel Disease Therapy in Patients Who Withheld Immunosuppressant Medications During COVID-19 #MMPMID33085972
  • Siegel CA; Christensen B; Kornbluth A; Rosh JR; Kappelman MD; Ungaro RC; Johnson DF; Chapman S; Wohl DA; Mantzaris GJ
  • J Crohns Colitis 2020[Oct]; 14 (14 Suppl 3): S769-S773 PMID33085972show ga
  • Patients with inflammatory bowel diseases [IBD] are frequently treated with immunosuppressant medications. During the coronavirus disease 2019 [COVID-19] pandemic, recommendations for IBD management have included that patients should stay on their immunosuppressant medications if they are not infected with the severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], but to temporarily hold these medications if symptomatic with COVID-19 or asymptomatic but have tested positive for SARS-CoV-2. As more IBD patients are infected globally, it is important to also understand how to manage IBD medications during convalescence while an individual with IBD is recovering from COVID-19. In this review, we address the differences between a test-based versus a symptoms-based strategy as related to COVID-19, and offer recommendations on when it is appropriate to consider restarting IBD therapy in patients testing positive for SARS-CoV-2 or with clinical symptoms consistent with COVID-19. In general, we recommend a symptoms-based approach, due to the current lack of confidence in the accuracy of available testing and the clinical significance of prolonged detection of virus via molecular testing.
  • |*Betacoronavirus/isolation & purification[MESH]
  • |*Clinical Laboratory Techniques[MESH]
  • |*Immunocompromised Host[MESH]
  • |Asymptomatic Infections[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Coronavirus Infections/diagnosis/*immunology/*prevention & control[MESH]
  • |Drug Administration Schedule[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/*administration & dosage/therapeutic use[MESH]
  • |Inflammatory Bowel Diseases/complications/*drug therapy/immunology[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/diagnosis/*immunology/*prevention & control[MESH]
  • |Risk Assessment[MESH]


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