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10.1021/acs.jproteome.0c00671

http://scihub22266oqcxt.onion/10.1021/acs.jproteome.0c00671
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33084340!ä!33084340

suck abstract from ncbi


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pmid33084340      J+Proteome+Res 2020 ; 19 (11): 4374-4379
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  • The COVID-19 Pandemic from a Human Genetic Perspective #MMPMID33084340
  • Zhang YM; Wang L; Liu XZ; Zhang H
  • J Proteome Res 2020[Nov]; 19 (11): 4374-4379 PMID33084340show ga
  • The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted a large portion of the world population. From a virus genetic perspective, a recent study described what genomic data revealed about the origin and emergence of SARS-CoV-2, proposing stronger action against illegal wildlife trade. In the current "big data" era, an increasing number of large-scale, multidimensional omics data sets were publicly available. Herein, we review how human genetics tells us about the transmission, pathogenesis, susceptibility, severity, and drug prioritization of COVID-19. We further drafted a genetic roadmap of COVID-19, which was also expected to be applicable to other viruses with known receptors. Our review provides insights into the way of understanding a pandemic from a human genetic perspective.
  • |*Coronavirus Infections/drug therapy/genetics/physiopathology/transmission[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/drug therapy/genetics/physiopathology/transmission[MESH]
  • |Animals[MESH]
  • |Animals, Wild[MESH]
  • |Antiviral Agents/administration & dosage/therapeutic use[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Genetic Predisposition to Disease[MESH]
  • |Humans[MESH]
  • |Organ Specificity[MESH]


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