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suck abstract from ncbi

pmid3307850      Appl+Pathol 1987 ; 5 (2): 88-94
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  • Recurrent and de novo glomerulonephritis in allografted kidneys: aspects of ultrastructural diagnosis #MMPMID3307850
  • Tornroth T
  • Appl Pathol 1987[]; 5 (2): 88-94 PMID3307850show ga
  • Allograft glomerulonephritis (GN) is a noteworthy alternative in the differential diagnosis of renal graft dysfunction. The true frequency of allograft GN is unknown; a rough estimate is 5-15%. The highest rates of recurrence (100-20%) have been reported, in decreasing order of frequency, in mesangiocapillary GN (MCGN) type 2, IgA nephropathy, MCGN type 1, and focal segmental glomerulosclerosis (FSGS). In addition, in about 2% of allografts membranous GN (MGN) occurs as a de novo lesion. Electron microscopy has proved valuable in detecting early or mild MGN, MCGN type 2 and FSGS, and in differentiating between MCGN type 1 and allograft (rejection) glomerulopathy. Even with the aid of electron microscopy, however, the demarcation between MCGN type 1 and allograft glomerulopathy may prove impossible. The finding of prominent mesangial deposits (in an otherwise normal allograft), is highly suggestive of recurrent IgA nephropathy.
  • |*Kidney Transplantation[MESH]
  • |Glomerulonephritis, IGA/pathology[MESH]
  • |Glomerulonephritis/classification/*pathology[MESH]
  • |Glomerulosclerosis, Focal Segmental/pathology[MESH]
  • |Humans[MESH]
  • |Kidney/ultrastructure[MESH]
  • |Membranes/pathology[MESH]
  • |Microscopy, Electron[MESH]


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