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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Eur+J+Clin+Microbiol+Infect+Dis 2021 ; 40 (4): 897-900 Nephropedia Template TP
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Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness #MMPMID33078222
Pegoraro M; Militello V; Salvagno GL; Gaino S; Bassi A; Caloi C; Peretti A; Bizzego S; Poletto L; Bovo C; Lippi G; Lo Cascio G
Results of three rapid immunochromatographic tests (ICTs) were compared with those obtained with two automated immunoassays for evaluation of their usefulness. One hundred fifty-nine patients and 67 healthy volunteers were included. Different assays demonstrate 41-45% of diagnostic sensitivities and 91-98% of specificities, with substantial agreement (89.3-91.2%), but a high percentage of weak positive results (13-22%) was observed with ICTs. ICTs performances were comparable to those of automated immunoassays. ICTs could have a role as screening approach due to their easy usability. Subjective interpretation, significant rate of uncertain results, uncertainty on viral antigens source are undoubtedly drawbacks.