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10.1007/s10096-020-04040-1

http://scihub22266oqcxt.onion/10.1007/s10096-020-04040-1
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33078222!7572234!33078222
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suck abstract from ncbi


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pmid33078222      Eur+J+Clin+Microbiol+Infect+Dis 2021 ; 40 (4): 897-900
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  • Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness #MMPMID33078222
  • Pegoraro M; Militello V; Salvagno GL; Gaino S; Bassi A; Caloi C; Peretti A; Bizzego S; Poletto L; Bovo C; Lippi G; Lo Cascio G
  • Eur J Clin Microbiol Infect Dis 2021[Apr]; 40 (4): 897-900 PMID33078222show ga
  • Results of three rapid immunochromatographic tests (ICTs) were compared with those obtained with two automated immunoassays for evaluation of their usefulness. One hundred fifty-nine patients and 67 healthy volunteers were included. Different assays demonstrate 41-45% of diagnostic sensitivities and 91-98% of specificities, with substantial agreement (89.3-91.2%), but a high percentage of weak positive results (13-22%) was observed with ICTs. ICTs performances were comparable to those of automated immunoassays. ICTs could have a role as screening approach due to their easy usability. Subjective interpretation, significant rate of uncertain results, uncertainty on viral antigens source are undoubtedly drawbacks.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibodies, Viral/*immunology[MESH]
  • |COVID-19 Nucleic Acid Testing[MESH]
  • |COVID-19 Serological Testing/*methods[MESH]
  • |COVID-19/*diagnosis/immunology[MESH]
  • |Child[MESH]
  • |Coronavirus Nucleocapsid Proteins/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoassay/*methods[MESH]
  • |Immunoglobulin A/immunology[MESH]
  • |Immunoglobulin G/immunology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Phosphoproteins/immunology[MESH]
  • |SARS-CoV-2/immunology[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Spike Glycoprotein, Coronavirus/*immunology[MESH]


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