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10.3390/v12101169

http://scihub22266oqcxt.onion/10.3390/v12101169
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33076391!7602620!33076391
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suck abstract from ncbi


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pmid33076391      Viruses 2020 ; 12 (10): ä
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  • An Outbreak of a Respiratory Disorder at a Russian Swine Farm Associated with the Co-Circulation of PRRSV1 and PRRSV2 #MMPMID33076391
  • Raev S; Yuzhakov A; Bulgakov A; Kostina L; Gerasianinov A; Verkhovsky O; Zaberezhny A; Aliper T
  • Viruses 2020[Oct]; 12 (10): ä PMID33076391show ga
  • We conducted a cross-sectional study to identify the major respiratory pathogen responsible for an outbreak of respiratory disease at a swine farm in West Siberia in 2019. We discovered that the peak of morbidity and mortality coincided with a high level of porcine reproductive and respiratory syndrome virus (PRRSV) 1 and 2-related viremia. Based on longer PRRSV2 viremia, the dominant role of PRRSV2 over PRRSV1 in the outbreak was assumed. Phylogenetic analysis revealed that the PRRSV1 strain belonged to sub-genotype 2-one of the predominant groups of genotype 1 PRRSVs in Russia. A partial open reading frame 7 sequence of the PRRSV2 isolate demonstrated a high identity with modified live vaccine-related strains from Denmark (93%) and wild-type VR2332 (92%). We identified the first instance of PRRSV1/PRRSV2 mixed infection in Russia. This finding indicates that further field investigations are needed to access PRRSV2 epidemiology in eastern Europe.
  • |Animals[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Disease Outbreaks/*veterinary[MESH]
  • |Farms[MESH]
  • |Genetic Variation[MESH]
  • |Genotype[MESH]
  • |Open Reading Frames[MESH]
  • |Phylogeny[MESH]
  • |Porcine Reproductive and Respiratory Syndrome/*epidemiology/mortality/virology[MESH]
  • |Porcine respiratory and reproductive syndrome virus/classification/*pathogenicity[MESH]
  • |Siberia/epidemiology[MESH]


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