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10.1016/j.ijid.2020.10.036

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.10.036
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suck abstract from ncbi


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pmid33075539      Int+J+Infect+Dis 2021 ; 102 (ä): 63-69
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  • SARS-CoV-2 seroprevalence among health care workers in a New York City hospital: A cross-sectional analysis during the COVID-19 pandemic #MMPMID33075539
  • Venugopal U; Jilani N; Rabah S; Shariff MA; Jawed M; Mendez Batres A; Abubacker M; Menon S; Pillai A; Shabarek N; Kasubhai M; Dimitrov V; Menon V
  • Int J Infect Dis 2021[Jan]; 102 (ä): 63-69 PMID33075539show ga
  • BACKGROUND: New York City (NYC) has endured the greatest burden of COVID-19 infections in the US. Health inequities in South Bronx predisposed this community to a large number of infectious cases, hospitalizations, and mortality. Health care workers (HCWs) are at a high risk of exposure to the infection. This study aims to assess seroprevalence and the associated characteristics of consenting HCWs from an NYC public hospital. METHODS: This cross-sectional study includes serum samples for qualitative SARS-CoV-2 antibody testing with nasopharyngeal swabs for SARS-CoV-2; PCR and completion of an online survey capturing demographics, COVID-19 symptoms during the preceding months on duty, details of healthcare and community exposure, and travel history were collected from consenting participants in May 2020. Participants' risk of exposure to COVID-19 infection in the hospital and in the community was defined based on CDC guidelines. Travel history to high-risk areas was also considered an additional risk. The Odds Ratio with bivariable and multivariable logistic regression was used to assess characteristics associated with seroprevalence. RESULTS: A total of 500 HCW were tested, 137 (27%) tested positive for the SARS-CoV-2 antibody. Symptomatic participants had a 75% rate of seroconversion compared to those without symptoms. Subjects with anosmia and ageusia had increased odds of seroconversion in comparison to those without these symptoms. Community exposure was 34% among those who had positive antibodies. CONCLUSION: Seroprevalence among HCWs was high compared to the community at the epicenter of the pandemic. Further studies to evaluate sustained adaptive immunity in this high-risk group will guide our response to a future surge.
  • |*COVID-19 Serological Testing[MESH]
  • |*Health Personnel[MESH]
  • |Adult[MESH]
  • |COVID-19 Nucleic Acid Testing[MESH]
  • |COVID-19/diagnosis/*epidemiology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Hospitals, Urban[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |New York City/epidemiology[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]


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