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Obesity and COVID-19: A jigsaw puzzle with still missing pieces #MMPMID33073512
Michalakis K; Panagiotou G; Ilias I; Pazaitou-Panayiotou K
Clin Obes 2021[Feb]; 11 (1): e12420 PMID33073512show ga
Apart from posing various mechanical and medical issues compromising general health, obesity is a major factor for respiratory tract infections, due to specific inflammation and immunological compromise. The burden of obesity on morbidity and mortality of SARS-CoV-2 infection/COVID-19 is considerable. Herein, we aimed to search the literature and present to the readers pathophysiologic pathways that may associate obesity and COVID-19. We present potential mechanisms, which might partly explain why patients with obesity are more prone to suffer from respiratory infections in the context of COVID-19. Better understanding of these pathways could eventually guide management strategies and therapies for COVID-19 in the future.