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10.1016/j.mayocpiqo.2020.09.010

http://scihub22266oqcxt.onion/10.1016/j.mayocpiqo.2020.09.010
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33073177!7550090!33073177
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suck abstract from ncbi


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pmid33073177      Mayo+Clin+Proc+Innov+Qual+Outcomes 2020 ; 4 (6): 759-763
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  • Time to Treat: Applying Lessons Learned from Other Viral Syndromes to SARS-CoV-2 #MMPMID33073177
  • Stevens RW; Rivera CG; Saleh OA
  • Mayo Clin Proc Innov Qual Outcomes 2020[Dec]; 4 (6): 759-763 PMID33073177show ga
  • In many different infectious syndromes, most notably several viral conditions, time to therapy initiation from symptom onset has been identified as a critical component contributing to the success of therapy. Regarding COVID-19, several therapeutic antivirals, both repurposed and novel, have been evaluated for overall safety and efficacy. As the literature related to these therapies has expanded recently, a wide array of trial designs, time to therapy initiation thresholds, and clinical outcomes in regard to time to initiation have been reported. We describe the potential effects of time to therapy initiation on outcomes in patients with COVID-19 and detail the existing data surrounding this topic in relation to remdesivir, convalescent plasma, lopinavir/ritonavir, and hydroxychloroquine.
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