Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.medcle.2020.06.024 http://scihub22266oqcxt.onion/10.1016/j.medcle.2020.06.024 33072869!7546238!33072869     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Clin+(Engl+Ed) 2020 ; 155 (9): 375-381 Nephropedia Template TP {{tp|p=33072869|t=2020. Therapeutic agents tested in 238 COVID-19 hospitalized patients and their relationship with mortality |pdf=|usr=}}{{33072869}} gab.com Text Therapeutic agents tested in 238 COVID-19 hospitalized patients and their relationship with mortality JO: Med Clin (Engl Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33072869 #FOAvip BACKGROUND AND OBJECTIVES: In the last months great efforts have been developed to evaluate the more efficient therapeutic agents in the management of patients with COVID-19. Currently, no specific drug combination has consistently demonstrated an association with mortality. The aim of this study was to assess the pattern of associations observed between the different in-hospital treatments administered to a series of 238 patients admitted for COVID-19 and their relationship with mortality. METHODS: The electronic medical records of patients that discharged or died from COVID-19 in the Hospital Universitario San Cecilio (Granada, Spain) between March 16 and April 10, 2020 were analysed. From these records, information was obtained on sex, age, comorbidities at admission, clinical information, analytical parameters, imaging tests and empirical treatments used. The outcome variable was the in-hospital mortality. To estimate the associations between the different therapeutic alternatives and the risk of mortality, Hazard Ratios adjusted for age, sex, previous pathologies and severity at discharge were estimated using Cox Regression models. RESULTS: The most frequently used combination of drugs was low molecular weight heparins, hydroxychloroquine, and ritonavir/lopinavir. None of the analysed treatments showed independent association with mortality. The drugs that showed a greater inverse association with mortality were tocilizumab and corticoids. CONCLUSIONS: The observed association patterns are consistent with previous literature. It seems necessary to design randomized controlled clinical trials that evaluate the possible protector effect of tocilizumab and corticoids in the risk of mortality for some subgroups of COVID-19 hospitalized patients. Twit Text FOAVip Therapeutic agents tested in 238 COVID-19 hospitalized patients and their relationship with mortality ????Med Clin (Engl Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33072869 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33072869 #FOAvip English Wikipedia <ref>{{Cite pmid|33072869}}</ref> Therapeutic agents tested in 238 COVID-19 hospitalized patients and their relationship with mortality #MMPMID33072869 Rivera-Izquierdo M; Valero-Ubierna MDC; R-delAmo JL; Fernandez-Garcia MA; Martinez-Diz S; Tahery-Mahmoud A; Rodriguez-Camacho M; Gamiz-Molina AB; Barba-Gyengo N; Gamez-Baeza P; Cabrero-Rodriguez C; Guirado-Ruiz PA; Martin-Romero DT; Lainez-Ramos-Bossini AJ; Sanchez-Perez MR; Mancera-Romero J; Garcia-Martin M; Martin-delosReyes LM; Martinez-Ruiz V; Jimenez-Mejias E Med Clin (Engl Ed) 2020[Nov]; 155 (9): 375-381 PMID33072869show ga BACKGROUND AND OBJECTIVES: In the last months great efforts have been developed to evaluate the more efficient therapeutic agents in the management of patients with COVID-19. Currently, no specific drug combination has consistently demonstrated an association with mortality. The aim of this study was to assess the pattern of associations observed between the different in-hospital treatments administered to a series of 238 patients admitted for COVID-19 and their relationship with mortality. METHODS: The electronic medical records of patients that discharged or died from COVID-19 in the Hospital Universitario San Cecilio (Granada, Spain) between March 16 and April 10, 2020 were analysed. From these records, information was obtained on sex, age, comorbidities at admission, clinical information, analytical parameters, imaging tests and empirical treatments used. The outcome variable was the in-hospital mortality. To estimate the associations between the different therapeutic alternatives and the risk of mortality, Hazard Ratios adjusted for age, sex, previous pathologies and severity at discharge were estimated using Cox Regression models. RESULTS: The most frequently used combination of drugs was low molecular weight heparins, hydroxychloroquine, and ritonavir/lopinavir. None of the analysed treatments showed independent association with mortality. The drugs that showed a greater inverse association with mortality were tocilizumab and corticoids. CONCLUSIONS: The observed association patterns are consistent with previous literature. It seems necessary to design randomized controlled clinical trials that evaluate the possible protector effect of tocilizumab and corticoids in the risk of mortality for some subgroups of COVID-19 hospitalized patients. äTherapeutic agents tested in 238 COVID-19 hospitalized patients and th(epmc).pdf DeepDyve Pubget Overpricing