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10.3389/fonc.2020.562625

http://scihub22266oqcxt.onion/10.3389/fonc.2020.562625
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suck abstract from ncbi


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pmid33072589      Front+Oncol 2020 ; 10 (ä): 562625
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  • Case Report: Tocilizumab for the Treatment of SARS-CoV-2 Infection in a Patient With Aplastic Anemia #MMPMID33072589
  • Keiffer G; French Z; Wilde L; Filicko-O'Hara J; Gergis U; Binder AF
  • Front Oncol 2020[]; 10 (ä): 562625 PMID33072589show ga
  • While cytokine storm develops in a minority of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, novel treatment approaches are desperately needed for those in whom it does. Tocilizumab, an interleukin-6 receptor antibody, has been utilized for the treatment of cytokine storm in a number of severe inflammatory conditions, including in patients with severe coronavirus disease 2019 (COVID-19). Here, we present the first published case utilizing this therapy in a patient with underlying immunodeficiency. Our patient with aplastic anemia developed cytokine storm due to COVID-19 manifested by fever, severe hypoxia, pulmonary infiltrates, and elevated inflammatory markers. Following treatment with tocilizumab, cytokine storm resolved, and the patient was ultimately safely discharged from the hospital.
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