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10.3389/fimmu.2020.564925

http://scihub22266oqcxt.onion/10.3389/fimmu.2020.564925
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33072103!7533543!33072103
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suck abstract from ncbi


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pmid33072103      Front+Immunol 2020 ; 11 (ä): 564925
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  • Immunopathogenesis of COVID-19: Summary and Possible Interventions #MMPMID33072103
  • Jacques FH; Apedaile E
  • Front Immunol 2020[]; 11 (ä): 564925 PMID33072103show ga
  • Since the onset of the COVID-19 pandemic in the fall of 2019 over 4 million people have been infected and over 280,000 have died (1). Information about the SARS-CoV2 virus is evolving rapidly. At this time there are no interventions proven to be effective for cases infected with SARS-CoV2. Current knowledge about the clinical and laboratory manifestations of COVID-19 infection is reviewed and combined with knowledge about the immunopathogenic mechanisms of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV1) and Middle East Respiratory Syndrome (MERS) to formulate theories and suggest possible therapeutic interventions. SARS-CoV2 immunopathogenic mechanisms vary from immunosuppression that initially enables viral escape to a hyperinflammatory immune response. Ultimately therapeutic intervention will be phase dependent.
  • |*Coronavirus Infections/epidemiology/immunology/therapy[MESH]
  • |*Immunosuppression Therapy[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/epidemiology/immunology/therapy[MESH]
  • |Betacoronavirus/*immunology[MESH]
  • |COVID-19[MESH]
  • |Humans[MESH]


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