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10.1016/j.bios.2020.112679 http://scihub22266oqcxt.onion/10.1016/j.bios.2020.112679 33069957!7545244!33069957     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biosens+Bioelectron 2021 ; 171 (ä): 112679 Nephropedia Template TP {{tp|p=33069957|t=2021. Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform |pdf=|usr=}}{{33069957}} gab.com Text Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform JO: Biosens Bioelectron http://www.kidney.de/pget.php?&tw=1&pmid=33069957 #FOAvip The 2019 SARS CoV-2 (COVID-19) pandemic has illustrated the need for rapid and accurate diagnostic tests. In this work, a multiplexed grating-coupled fluorescent plasmonics (GC-FP) biosensor platform was used to rapidly and accurately measure antibodies against COVID-19 in human blood serum and dried blood spot samples. The GC-FP platform measures antibody-antigen binding interactions for multiple targets in a single sample, and has 100% selectivity and sensitivity (n = 23) when measuring serum IgG levels against three COVID-19 antigens (spike S1, spike S1S2, and the nucleocapsid protein). The GC-FP platform yielded a quantitative, linear response for serum samples diluted to as low as 1:1600 dilution. Test results were highly correlated with two commercial COVID-19 antibody tests, including an enzyme linked immunosorbent assay (ELISA) and a Luminex-based microsphere immunoassay. To demonstrate test efficacy with other sample matrices, dried blood spot samples (n = 63) were obtained and evaluated with GC-FP, yielding 100% selectivity and 86.7% sensitivity for diagnosing prior COVID-19 infection. The test was also evaluated for detection of multiple immunoglobulin isotypes, with successful detection of IgM, IgG and IgA antibody-antigen interactions. Last, a machine learning approach was developed to accurately score patient samples for prior COVID-19 infection, using antibody binding data for all three COVID-19 antigens used in the test. Twit Text FOAVip Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform ????Biosens Bioelectron http://www.kidney.de/pget.php?&tw=1&pmid=33069957 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33069957 #FOAvip English Wikipedia <ref>{{Cite pmid|33069957}}</ref> Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform #MMPMID33069957 Cady NC; Tokranova N; Minor A; Nikvand N; Strle K; Lee WT; Page W; Guignon E; Pilar A; Gibson GN Biosens Bioelectron 2021[Jan]; 171 (ä): 112679 PMID33069957show ga The 2019 SARS CoV-2 (COVID-19) pandemic has illustrated the need for rapid and accurate diagnostic tests. In this work, a multiplexed grating-coupled fluorescent plasmonics (GC-FP) biosensor platform was used to rapidly and accurately measure antibodies against COVID-19 in human blood serum and dried blood spot samples. The GC-FP platform measures antibody-antigen binding interactions for multiple targets in a single sample, and has 100% selectivity and sensitivity (n = 23) when measuring serum IgG levels against three COVID-19 antigens (spike S1, spike S1S2, and the nucleocapsid protein). The GC-FP platform yielded a quantitative, linear response for serum samples diluted to as low as 1:1600 dilution. Test results were highly correlated with two commercial COVID-19 antibody tests, including an enzyme linked immunosorbent assay (ELISA) and a Luminex-based microsphere immunoassay. To demonstrate test efficacy with other sample matrices, dried blood spot samples (n = 63) were obtained and evaluated with GC-FP, yielding 100% selectivity and 86.7% sensitivity for diagnosing prior COVID-19 infection. The test was also evaluated for detection of multiple immunoglobulin isotypes, with successful detection of IgM, IgG and IgA antibody-antigen interactions. Last, a machine learning approach was developed to accurately score patient samples for prior COVID-19 infection, using antibody binding data for all three COVID-19 antigens used in the test. |*Clinical Laboratory Techniques[MESH] |Antibodies, Viral/*blood/immunology[MESH] |Betacoronavirus/*immunology/isolation & purification[MESH] |Biosensing Techniques/*instrumentation[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Coronavirus Infections/*blood/diagnosis/immunology[MESH] |Dried Blood Spot Testing[MESH] |Equipment Design[MESH] |Fluorescence[MESH] |Humans[MESH] |Immunoglobulin G/blood/immunology[MESH] |Lab-On-A-Chip Devices[MESH] |Pandemics[MESH] |Pneumonia, Viral/*blood/diagnosis/immunology[MESH] |SARS-CoV-2[MESH]Multiplexed detection and quantification of human antibody response to(epmc).pdf DeepDyve Pubget Overpricing