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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Virol+Sin 2020 ; 35 (6): 673-684 Nephropedia Template TP
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A Crowned Killer s Resume: Genome, Structure, Receptors, and Origin of SARS-CoV-2 #MMPMID33068260
Wang S; Trilling M; Sutter K; Dittmer U; Lu M; Zheng X; Yang D; Liu J
Virol Sin 2020[Dec]; 35 (6): 673-684 PMID33068260show ga
The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Chinese scientists and physicians rapidly identified the causative pathogen, which turned out to be a novel betacoronavirus with high sequence similarities to bat and pangolin coronaviruses. The scientific community has ignited tremendous efforts to unravel the biological underpinning of SARS-CoV-2, which constitutes the foundation for therapy and vaccine development strategies. Here, we summarize the current state of knowledge on the genome, structure, receptor, and origin of SARS-CoV-2.