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10.1016/j.jstrokecerebrovasdis.2020.105225

http://scihub22266oqcxt.onion/10.1016/j.jstrokecerebrovasdis.2020.105225
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33066917!7405833!33066917
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suck abstract from ncbi


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pmid33066917      J+Stroke+Cerebrovasc+Dis 2020 ; 29 (11): 105225
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  • COVID-19 and Stroke: Incidence and Etiological Description in a High-Volume Center #MMPMID33066917
  • Requena M; Olive-Gadea M; Muchada M; Garcia-Tornel A; Deck M; Juega J; Boned S; Rodriguez-Villatoro N; Pinana C; Pagola J; Rodriguez-Luna D; Hernandez D; Rubiera M; Tomasello A; Molina CA; Ribo M
  • J Stroke Cerebrovasc Dis 2020[Nov]; 29 (11): 105225 PMID33066917show ga
  • BACKGROUND: An increased rate of thrombotic events has been associated to Coronavirus Disease 19 (COVID-19) with a variable rate of acute stroke. Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist. METHODS: We performed a single-center analysis of a prospective mandatory database. We studied all patients with confirmed COVID-19 and stroke diagnoses from March 2(nd) to April 30(th). Demographic, clinical, and imaging data were prospectively collected. Final diagnosis was determined after full diagnostic work-up unless impossible due to death. RESULTS: Of 2050 patients with confirmed SARS-CoV-2 infection, 21 (1.02%) presented an acute ischemic stroke 21 and 4 (0.2%) suffered an intracranial hemorrhage. After the diagnostic work-up, in 60.0% ischemic and all hemorrhagic strokes patients an etiology non-related with COVID-19 was identified. Only in 6 patients the stroke cause was considered possibly related to COVID-19, all of them required mechanical ventilation before stroke onset. Ten patients underwent endovascular treatment; compared with patients who underwent EVT in the same period, COVID-19 was an independent predictor of in-hospital mortality (50% versus 15%; Odds Ratio, 6.67; 95% CI, 1.1-40.4; p 0.04). CONCLUSIONS: The presence of acute stroke in patients with COVID-19 was below 2% and most of them previously presented established stroke risk factors. Without other potential cause, stroke was an uncommon complication and exclusive of patients with a severe pulmonary injury. The presence of COVID-19 in patients who underwent EVT was an independent predictor of in-hospital mortality.
  • |*Hospitals, High-Volume[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology/mortality/therapy/virology[MESH]
  • |Databases, Factual[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Host-Pathogen Interactions[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/mortality/therapy/virology[MESH]
  • |Prognosis[MESH]
  • |Prospective Studies[MESH]
  • |Risk Assessment[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Spain[MESH]
  • |Stroke/*epidemiology/mortality/therapy/virology[MESH]


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